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acquired heart defects

Содержание

Valvular heart disease is any disease process involving one or more of the valves of the heart (the aortic and mitral valves on the left and the pulmonary and

Слайды и текст этой презентации

Слайд 1acquired heart defects

acquired heart defects

Слайд 3 Valvular heart disease is any disease process involving

one or more of the valves of the heart (the

aortic and mitral valves on the left and the pulmonary and tricuspid valves on the right). Valve problems may be congenital (inborn) or acquired (due to another cause later in life
Valvular heart disease is any disease process involving one or more of the valves of

Слайд 4MITRAL VALVE STENOSIS
Mitral stenosis (MS) refers to narrowing of the

mitral valve orifice, resulting in impedance of filling of the

left ventricle in diastole.
MITRAL VALVE STENOSISMitral stenosis (MS) refers to narrowing of the mitral valve orifice, resulting in impedance of

Слайд 5ETIOLOGY
Primarily a result of rheumatic fever.
Infective endocarditis.
Systemic lupus erythematosus, rheumatoid

arthritis.
Severe calcification of the mitral annulus.
The association of atrial

septal defect with rheumatic mitral stenosis is called Lutembacher syndrome.

Epidemiology: The prevalence of rheumatic disease is higher in developing nations than in the United States. In India, for example, the prevalence is approximately 100-150 cases per 100,000, and in Africa the prevalence is 35 cases per 100,000.
ETIOLOGYPrimarily a result of rheumatic fever.Infective endocarditis.Systemic lupus erythematosus, rheumatoid arthritis.Severe calcification of the mitral annulus. The

Слайд 6Pathophysiology
Normal valve area: 4-6 cm2
Mild mitral stenosis:
MVA 1.5-2.5 cm2
Minimal

symptoms
Mod mitral stenosis
MVA 1.0-1.5 cm2 usually does not produce symptoms

at rest
Severe mitral stenosis
MVA < 1.0 cm2

PathophysiologyNormal valve area: 4-6 cm2Mild mitral stenosis: MVA 1.5-2.5 cm2Minimal symptomsMod mitral stenosisMVA 1.0-1.5 cm2 usually does

Слайд 7Pathophysiology
Patients with MS typically present more than 20

years after an episode of rheumatic fever. Single or recurrent

bouts of rheumatic carditis cause progressive thickening, scarring, and calcification of the mitral leaflets and chordae. Fusion of the commissures and chordae decreases the size of the mitral opening. This obstruction results in the development of a pressure gradient across the valve in diastole and causes an elevation in left atrial and pulmonary venous pressures.
Pathophysiology  Patients with MS typically present more than 20 years after an episode of rheumatic fever.

Слайд 8Pathophysiology
Elevated left atrial pressures lead to left atrial

enlargement, predisposing the patient to atrial fibrillation and arterial thromboembolism.

Elevated pulmonary venous pressure results in pulmonary congestion and pulmonary edema. In advanced mitral stenosis, patients develop pulmonary hypertension and right-sided heart failure.

Pathophysiology  Elevated left atrial pressures lead to left atrial enlargement, predisposing the patient to atrial fibrillation

Слайд 10Symptoms and sings
Dyspnea , cough.
Left sided failure.
Hemoptysis.
Palpitation, Atrial arrhythmias.
Cardialgia.
Systemic embolism.
Right

sided failure (Hepatic Congestion, Edema).



Symptoms and singsDyspnea , cough.Left sided failure.Hemoptysis.Palpitation, Atrial arrhythmias.Cardialgia.Systemic embolism.Right sided failure (Hepatic Congestion, Edema).

Слайд 11Objectively
Acrocyanosis , facies mitralis.
Palpation - «purring thrill» - it refers

to a vibration, like a cat's purring, due to mitral

stenosis .
Percussion – shifting boundaries of relative cardiac dullness up and right .

ObjectivelyAcrocyanosis , facies mitralis.Palpation - «purring thrill» - it refers to a vibration, like a cat's purring,

Слайд 13 Auscultation:
The auscultatory findings characteristic of mitral stenosis are

a loud first heart sound, an opening snap, and a

diastolic rumble.
The first heart sound is accentuated because of a wide closing excursion of the mitral leaflets. The intensity of the first heart sound diminishes as the valve becomes more fibrotic, calcified, and thickened.
The diastolic murmur of mitral stenosis is of low pitch, rumbling in character, and best heard at the apex with the patient in the left lateral position. It commences after the opening snap of the mitral valve, and the duration of the murmur correlates with the severity of the stenosis.
Auscultation:The auscultatory findings characteristic of mitral stenosis are a loud first heart sound, an opening

Слайд 14 Auscultation:
3. The second heart sound is normally split, and

the pulmonic component is accentuated if pulmonary hypertension is present.


4. A high-pitched decrescendo diastolic murmur secondary to pulmonary regurgitation (Graham Steell murmur) may be audible at the upper sternal border.
Pulse – tachycardia, pulsus differens.

Auscultation:3. The second heart sound is normally split, and the pulmonic component is accentuated if pulmonary

Слайд 15Chest radiographic findings suggestive of mitral stenosis include left atrial

enlargement prominent pulmonary vessels, redistribution of pulmonary vasculature to the

upper lobes, mitral valve calcification, and interstitial edema.

Diagnosis

Chest radiographic findings suggestive of mitral stenosis include left atrial enlargement prominent pulmonary vessels, redistribution of pulmonary

Слайд 16ECG: Р-mitrale – left atrial enlargement in I,II leads; atrial

fibrillation.

ECG: Р-mitrale – left atrial enlargement in I,II leads; atrial fibrillation.

Слайд 17Echocardiography
is the most specific and sensitive method of diagnosing and

quantifying the severity of mitral stenosis. Using a transthoracic 2-dimensional

echocardiogram, Doppler study, and color-flow Doppler imaging, the anatomic abnormalities of the stenotic valve (ie, thickening, mobility, motion, calcification), involvement of the subvalvular apparatus and the characteristic fusion of the commissures can be well defined.
Echocardiographyis the most specific and sensitive method of diagnosing and quantifying the severity of mitral stenosis. Using

Слайд 19With echocardiography, the size of the mitral valve orifice can

be precisely quantified. Important information about the ventricular and atrial

chamber sizes, the presence of a left atrial thrombus, measurement of transvalvular gradient, and pulmonary arterial pressure can also be obtained.
With the use of Doppler echocardiography, sufficient information can be obtained to develop a therapeutic plan, and, consequently, most patients do not require invasive procedures such as cardiac catheterization.
With echocardiography, the size of the mitral valve orifice can be precisely quantified. Important information about the

Слайд 20Transesophageal echocardiography
provides better quality images than transthoracic

echocardiography and is more accurate in assessing the anatomic features

of the valve and the presence of left atrial appendage thrombus.
Transesophageal echocardiography is indicated in patients before percutaneous mitral balloon valvotomy or cardioversion.
Transesophageal echocardiography  provides better quality images than transthoracic echocardiography and is more accurate in assessing the

Слайд 21






Transesophageal echocardiogram with continuous wave Doppler interrogation across the mitral

valve demonstrating an increased mean gradient of 16 mm Hg

consistent with severe mitral stenosis.
Transesophageal echocardiogram with continuous wave Doppler interrogation across the mitral valve demonstrating an increased mean gradient of

Слайд 22Laboratory Studies
perform routine baseline tests such as CBC count, electrolyte

status, and renal and liver function tests.

Laboratory Studiesperform routine baseline tests such as CBC count, electrolyte status, and renal and liver function tests.

Слайд 23Complications

Hemoptysis;
Pulmonary edema;
Atrial fibrillation;
Systemic embolization (10-25%);
Congestive heart failure;
Pulmonary infections.

ComplicationsHemoptysis;Pulmonary edema;Atrial fibrillation;Systemic embolization (10-25%);Congestive heart failure;Pulmonary infections.

Слайд 24Differential Diagnosis
Mitral insufficiency.
Aortic insufficiency.
Tuberculosis, bronchiectasis .
Primary pulmonary hypertension.
Atrial septal

defect.

Differential Diagnosis Mitral insufficiency.Aortic insufficiency.Tuberculosis, bronchiectasis .Primary pulmonary hypertension.Atrial septal defect.

Слайд 25Treatment
Regime depends on the severity of chronic heart failure.
Diet №

10-A or 10 (depending on the severity of CHF).
MEDICAL:
Treatment

of the main disease (chronic rheumatic heart disease).
Treatment of cardiac arrhythmias and heart failure.
Anticoagulation with warfarin is indicated to prevent thromboembolism when atrial fibrillation is present, if there is a prior history of thromboembolism, or a thrombus is detected in the left atrium Endocarditis prophylaxis.



TreatmentRegime depends on the severity of chronic heart failure.Diet № 10-A or 10 (depending on the severity

Слайд 26Surgical Therapy
Mitral commissurotomy
Mitral Valve Replacement
Mechanical
Bioprosthetic

Invasive therapy should be considered

for all patients with symptomatic mitral stenosis. Percutaneous mitral balloon

valvotomy and surgical commissurotomy provide equivalent immediate and long-term outcome results and delay the need for mitral valve replacement.
Surgical TherapyMitral commissurotomyMitral Valve ReplacementMechanicalBioprosthetic Invasive therapy should be considered for all patients with symptomatic mitral stenosis.

Слайд 27Mitral Valve Replacement Mechanical Valve

Mitral Valve Replacement  Mechanical Valve

Слайд 28Mitral Valve Replacement Bioprosthetic Valve

Mitral Valve Replacement  Bioprosthetic Valve

Слайд 29Mitral regurgitation
is leakage of blood from the left ventricle

into the left atrium during systole. It is caused by

various mechanisms related to structural or functional abnormalities of the mitral apparatus, adjacent myocardium, or both.
Mitral regurgitation   is leakage of blood from the left ventricle into the left atrium during

Слайд 30Epidemiology
Significant mitral valve regurgitation occurs in about 2% of the

population with a similar prevalence in males and females.

EpidemiologySignificant mitral valve regurgitation occurs in about 2% of the population with a similar prevalence in males

Слайд 31Etiology
Rheumatic fever.
Infective endocarditis.
Aterosclerosis.
Myxomatous degeneration.
Chordal rupture.
Coronary artery disease.
Cardiomyopathy.

EtiologyRheumatic fever.Infective endocarditis.Aterosclerosis.Myxomatous degeneration.Chordal rupture.Coronary artery disease.Cardiomyopathy.

Слайд 32Pathophysiology
Significant MR leads to volume overload of the

left ventricle, because it has to accommodate both the stroke

volume and regurgitant volume with each heartbeat. To compensate, the left ventricle dilates and becomes hyperdynamic. In acute severe MR, the left atrial and pulmonary venous pressures increase quickly, leading to pulmonary congestion and pulmonary edema.
Pathophysiology  Significant MR leads to volume overload of the left ventricle, because it has to accommodate

Слайд 33 In chronic MR, a gradual increase in left

atrial size and compliance compensate so that left atrial and

pulmonary venous pressures do not increase until late in the course of the disease. Progressive left ventricular dilation eventually leads to an increase in afterload, contractile dysfunction, and heart failure. Left atrial enlargement predisposes the patient to atrial fibrillation and arterial thromboembolism. In long-standing MR, patients may develop pulmonary hypertension and right-sided heart failure.

In chronic MR, a gradual increase in left atrial size and compliance compensate so that

Слайд 35Signs and Symptoms
Patients with chronic, severe mitral regurgitation may remain

asymptomatic for years because the regurgitant volume load is well

tolerated as a result of compensatory ventricular and atrial dilation.
Dyspnea, fatigue, orthopnea, paroxysmal nocturnal dyspnea, and palpitations caused by atrial fibrillation. .
Cardialgia.

Signs and SymptomsPatients with chronic, severe mitral regurgitation may remain asymptomatic for years because the regurgitant volume

Слайд 36Objectively
Acrocyanosis, facies mitralis.
Palpation – apex beat displaced laterally.
Percussion -

displacement relative cardiac dullness to the left, up, down.
Auscultation –

S1 may be diminished in acute MR and chronic severe MR with defective valve leaflets. S3 may be present due to LV dysfunction or as a result of increased blood flow across the mitral valve. Blowing holosystolic murmur at the cardiac apex. S2 may be accentuated if pulmonary hypertension is present.
Objectively Acrocyanosis, facies mitralis.Palpation – apex beat displaced laterally.Percussion - displacement relative cardiac dullness to the left,

Слайд 37The chest radiograph demonstrates left atrial enlargement and cardiomegaly, 

pulmonary vascularity.

The chest radiograph demonstrates left atrial enlargement and cardiomegaly,  pulmonary vascularity.

Слайд 38ECG: enlargement LV, atrial fibrillation.

ECG: enlargement LV, atrial fibrillation.

Слайд 39Echocardiography: high-velocity jet in the LA during systole the severity

of the regurgitation is a function of the distance from

the valve that the jet can be detected. Hypertrophy and dilatation of LV and LA.
Echocardiography: high-velocity jet in the LA during systole the severity of the regurgitation is a function of

Слайд 40COMPLICATIONS
Hemoptysis;
Pulmonary edema;
Atrial fibrillation;
Thromboembolism.

COMPLICATIONS  Hemoptysis;Pulmonary edema;Atrial fibrillation;Thromboembolism.

Слайд 41Differential Diagnoses
Aortic Stenosis
Mitral Stenosis
Complications of Myocardial Infarction
Mitral Valve Prolapse
Ventricular Septal

Defect

Differential DiagnosesAortic StenosisMitral StenosisComplications of Myocardial InfarctionMitral Valve ProlapseVentricular Septal Defect

Слайд 42Treatment
Regime depends on the severity of chronic heart failure.
Diet №

10-A or 10 (depending on the severity of CHF).

MEDICAL:
Treatment

of the main disease (chronic rheumatic heart disease).
Treatment of cardiac arrhythmias and heart failure.
Anticoagulation with warfarin is indicated to prevent thromboembolism when atrial fibrillation is present, if there is a prior history of thromboembolism, or a thrombus is detected in the left atrium Endocarditis prophylaxis.

TreatmentRegime depends on the severity of chronic heart failure.Diet № 10-A or 10 (depending on the severity

Слайд 43Prognosis
after surgical treatment prognosis is favorable

Prognosis  after surgical treatment prognosis is favorable

Слайд 44Aortic Stenosis
Aortic stenosis refers
to obstruction

of flow at the level of the aortic valve and

does not include the subvalvular and supravalvular forms
of this disease.
Aortic Stenosis  Aortic stenosis refers  to obstruction of flow at the level of the aortic

Слайд 46Valvular Aortic stenosis
Valvular Aortic stenosis.

Valvular Aortic stenosisValvular Aortic stenosis.

Слайд 47Etiology
Rheumatic fever.
Degenerative calcific aortic stenosis.
Infective endocarditis.
Hypertrophic cardiomyopathy.

Aortic stenosis has several etiologies, including congenital (unicuspid

or bicuspid valve), calcific (due to degenerative changes), and rheumatic.

EtiologyRheumatic fever.Degenerative calcific aortic stenosis.Infective endocarditis.Hypertrophic cardiomyopathy.      Aortic stenosis has several etiologies,

Слайд 48Epidemiology
Degenerative calcific aortic stenosis usually manifests in individuals older than

75 years and occurs most frequently in males. Aortic sclerosis

(aortic valve calcification without obstruction to blood flow, considered a precursor of calcific degenerative calcific aortic stenosis) increases in incidence with age and is present in 29% of individuals older than 65 years and in 37% of individuals older than 75 years. Degenerative calcific aortic stenosis usually manifests in individuals older than 75 years and occurs most frequently in males.
EpidemiologyDegenerative calcific aortic stenosis usually manifests in individuals older than 75 years and occurs most frequently in

Слайд 50 Symptoms and signs
Common in asymptomatic adults.
Fatigue, dizziness, syncope.
Angina

pectoris.
Dyspnea.
Pulmonary edema.
Hemoptysis.

Symptoms and signsCommon in asymptomatic adults.Fatigue, dizziness, syncope. Angina pectoris.Dyspnea.Pulmonary edema.Hemoptysis.

Слайд 52Physical Examination
Pale skin or cyanosis.
On palpation – apex beat amplified

and shifted to the left.
On percussion – displacement of relative

cardiac dullness to the left, down.
Physical Examination Pale skin or cyanosis.On palpation – apex beat amplified and shifted to the left.On percussion

Слайд 53On auscultation – S1 is usually normal or soft. The

aortic component of the second heart sound, A2, is usually

diminished or absent, because the aortic valve is calcified and immobile and/or the aortic ejection is prolonged and it is obscured by the prolonged systolic ejection murmur. The presence of a normal or accentuated A2 speaks against the presence of severe aortic stenosis.
The classic crescendo-decrescendo harsh systolic murmur of aortic stenosis begins shortly after the first heart sound.
The intensity of the systolic murmur does not correspond to the severity of aortic stenosis; rather, the timing of the peak and the duration of the murmur corresponds to the severity of aortic stenosis.

On auscultation – S1 is usually normal or soft. The aortic component of the second heart sound,

Слайд 54Physical Examination
Pulsus parvus and tardus (Carotid Impulse).
Systolic hypertension can coexist

with aortic stenosis. However, a systolic blood pressure higher than

200 mm Hg is rare in patients with critical aortic stenosis.
Physical ExaminationPulsus parvus and tardus (Carotid Impulse).Systolic hypertension can coexist with aortic stenosis. However, a systolic blood

Слайд 55The cardiac size often is normal, with rounding of the

LV border and apex. Poststenotic dilatation of the ascending aorta

is common. Aortic valve calcification is found in almost all adults.

Chest Radiography

The cardiac size often is normal, with rounding of the LV border and apex. Poststenotic dilatation of

Слайд 56ECG: the principal finding is left ventricular hypertrophy , ST

depression exceeding 0.3 mV in patients with aortic stenosis indicates

LV strain and suggests severe LVH.
ECG: the principal finding is left ventricular hypertrophy , ST depression exceeding 0.3 mV in patients with

Слайд 57
Echocardiography: The following 3 echocardiographic findings are indicative of severe

aortic stenosis:
1. An echo-dense aortic valve with no cusp motion

(may be unreliable in congenital or rheumatic valvular stenosis).
2. A decrease in the maximal aortic cusp separation (< 8 mm in the adult).
3. The presence of otherwise unexplained LV hypertrophy.
Cardiac Catheterization and Coronary Arteriography- if clinical findings are not consistent with Doppler echocardiogram results, cardiac catheterization is recommended for further hemodynamic assessment.
Echocardiography: The following 3 echocardiographic findings are indicative of severe aortic stenosis:1. An echo-dense aortic valve with

Слайд 58Criteria for Determining Severity of Aortic Stenosis

Criteria for Determining Severity of Aortic Stenosis

Слайд 60 Differential Diagnoses
Mitral regurgitation.
Aortic regurgitation.
Tuberculosis, bronchiectasis.
Primary pulmonary hypertension.
Myocardial Infarction.
NB! Other

problems to be considered in patients with possible aortic stenosis

include supravalvaraortic stenosis, congenital subvalvar aortic stenosis, and hypertrophic obstructive cardiomyopathy.
Differential DiagnosesMitral regurgitation.Aortic regurgitation.Tuberculosis, bronchiectasis.Primary pulmonary hypertension.Myocardial Infarction.NB! Other problems to be considered in patients with

Слайд 61Treatment
Regime depends on the severity of chronic heart failure.
Diet №

10-A or 10 (depending on the severity of CHF).

MEDICAL:
Treatment

of the main disease (chronic rheumatic heart disease).
Treatment of cardiac arrhythmias and heart failure.

TreatmentRegime depends on the severity of chronic heart failure.Diet № 10-A or 10 (depending on the severity

Слайд 62Surgical Therapy
According to both the ACC/AHA and ESC/EACTS guidelines, aortic

valve replacement should be performed in all symptomatic patients with

severe aortic stenosis, regardless of LV function, as survival is better with surgical treatment than with medical treatment.
Surgical TherapyAccording to both the ACC/AHA and ESC/EACTS guidelines, aortic valve replacement should be performed in all

Слайд 63Surgical Therapy
Patient with symptomatic AS and valve gradient indicative of

moderate or severe stenosis(>50 mm Hg) should have valve replacement
Aortic

Balloon Valvuloplasty is useful in congenital aortic stenosis
Anticoagulants are required only if patient have atrial fibrillation or have valve replacement with mechanical prosthesis


Surgical TherapyPatient with symptomatic AS and valve gradient indicative of moderate or severe stenosis(>50 mm Hg) should

Слайд 64Prosthetic Heart Valves
Disc Valve
Bio-prosthetic Valve

Prosthetic Heart ValvesDisc ValveBio-prosthetic Valve

Слайд 65PROGNOSIS
The only definitive treatment for aortic stenosis

is aortic valve replacement. The development of symptoms due to

aortic stenosis provides a clear indication for replacement. For patients who are not candidates for aortic replacement, percutaneous aortic balloon valvuloplasty may provide some symptom relief.
Medical treatment (such as diuretic therapy) in aortic stenosis may provide temporary symptom relief but is generally not effective long term.
PROGNOSIS  The only definitive treatment for aortic stenosis is aortic valve replacement. The development of symptoms

Слайд 66Aortic regurgitation

Aortic regurgitation

Слайд 67Etiology
Acquired:
Rheumatic fever (60-80%).
Infective endocarditis.
Syphilitic aortitis.
Collagen vascular diseases.
Degenerative aortic valve

disease.
Relative aortic valve insufficiency due to increased LV cavity.
Trauma.
Congenital

causes - Bicuspid aortic valve is the most common congenital cause.
EtiologyAcquired:Rheumatic fever (60-80%).Infective endocarditis.Syphilitic aortitis.Collagen vascular diseases. Degenerative aortic valve disease.Relative aortic valve insufficiency due to increased

Слайд 68 Epidemiology

Although rheumatic heart disease is overall

the most common cause of AR worldwide, congenital and degenerative

valve abnormalities are the most common cause, with the age of detection peaking at 40-60 years. Estimates of the prevalence of AR of any severity range from 2-30%, but only 5-10% of patients with AR have severe disease, resulting in an overall prevalence of severe AR of less than 1% in the general population
Epidemiology   Although rheumatic heart disease is overall the most common cause of AR worldwide,

Слайд 70Symptoms and sings
Patients with chronic AR often have a long-standing

asymptomatic period that may last for several years.
Palpitations - Often

described as the sensation of having forceful heart beats, due to widened pulse pressure with hyperdynamic circulation
Uncomfortable awareness of the heartbeat
Shortness of breath - May not worsen with exertion in the early stages due to compensatory tachycardia with shortened diastole
Chest pain - Occurs if increased LV end-diastolic pressure compromises coronary perfusion pressure gradients
Headache pulsing character, dizziness, syncope.
Symptoms and singsPatients with chronic AR often have a long-standing asymptomatic period that may last for several

Слайд 71AR - Diagnosis

Austin-Flint murmur – vibrations of anterior mitral leaflet
Duroziez’s

sign – ‘to and fro’ femoral artery murmur
Quincke’s pulse –

capillary pulsation in finger tips
Traube’s sign – ‘pistol shot’ sound at femoral artery
De Musset’s sign – head bobbing
Visible enhanced carotid pulse "dance carotid"
AR - DiagnosisAustin-Flint murmur – vibrations of anterior mitral leafletDuroziez’s sign – ‘to and fro’ femoral artery

Слайд 72On palpation - the point of maximal heart beat may

be diffuse or hyperdynamic but is often displaced inferiorly and

toward the axilla.
On percussion - displacement of relative cardiac dullness to the left, down.
On auscultation - weakening or disappearance of II sound of the aorta.
A systolic murmur of the aorta occurs in diastole, usually as a high-pitched sound that is loudest at the left sternal border.
An Austin-Flint murmur may be present at the cardiac apex in severe AR; it is a low-pitched, mid-diastolic rumbling murmur due to blood jets from the AR striking the anterior leaflet of the mitral valve, which results in premature closure of the mitral leaflets.
On palpation - the point of maximal heart beat may be diffuse or hyperdynamic but is often

Слайд 73Pulsus- pulsus celer, tachycardia.
BP – Diastolic pressures are often lower

than 60 mm Hg, with pulse pressures often exceeding 100

mm Hg, although younger patients with more compliant vessels may have a less widened pulse pressure.
Pulsus- pulsus celer, tachycardia.BP – Diastolic pressures are often lower than 60 mm Hg, with pulse pressures

Слайд 74The structural abnormalities (aortic dilation, prosthetic valve dislodgement, aortic valvular

calcification) or functional compromise (pulmonary edema, cardiomegaly).
Chest radiography

The structural abnormalities (aortic dilation, prosthetic valve dislodgement, aortic valvular calcification) or functional compromise (pulmonary edema, cardiomegaly).

Слайд 75ECG: Left axis deviation , LV hypertrophy, LA enlargement.

ECG: Left axis deviation , LV hypertrophy, LA enlargement.

Слайд 76Echocardiography:
Aortic valve structure and morphology - Bileaflet versus trileaflet, flail,

thickening
Presence of vegetations or nodules - May require transesophageal echocardiography

in selected cases
Severity of AR
Color Doppler jet width
Regurgitant volume, fraction, and orifice area


Echocardiography:Aortic valve structure and morphology - Bileaflet versus trileaflet, flail, thickeningPresence of vegetations or nodules - May

Слайд 77Echocardiography:
Premature closure of the mitral valve (seen in severe AR)

and opening of the aortic valve (with severely elevated LV

end-diastolic pressure)
Pressure half-time - Usually less than 300-350 ms with significant AR
Associated lesions of the aorta - Including dilation, aneurysm, dissection, or ectasia
LV structure and function
LV hypertrophy and dilation
Ejection fraction (EF) and end-systolic dimension


Echocardiography:Premature closure of the mitral valve (seen in severe AR) and opening of the aortic valve (with

Слайд 78Transesophageal echocardiography
Severe aortic regurgitation

Transesophageal echocardiography Severe aortic regurgitation

Слайд 79Other methods of diagnostics:
Radionuclide imaging (may provide complementary clinical information,

including the AR regurgitant fraction and the LV/right ventricular (RV)

stroke volume ratio.
Aortic angiography (may provide useful information regarding the severity of the patient's AR).
Cardiac Catheterization.
Cardiac CT scanning and magnetic resonance imaging (MRI).



Other methods of diagnostics:Radionuclide imaging (may provide complementary clinical information, including the AR regurgitant fraction and the

Слайд 80Treatment
Regime depends on the severity of chronic heart failure.
Diet №

10-A or 10 (depending on the severity of CHF).
MEDICAL:
Treatment

of the main disease (chronic rheumatic heart disease).
Treatment chronic heart failure.



TreatmentRegime depends on the severity of chronic heart failure.Diet № 10-A or 10 (depending on the severity

Слайд 81Surgical Therapy
AORTIC VALVE REPLACEMENT

Surgical TherapyAORTIC VALVE REPLACEMENT

Слайд 82Trends in choice of prosthesis
· Age less than 55 years

- Aortic allograft or pulmonary autograft
· Age between 55-75 years

- Mechanical prosthesis
· Age greater than 75 years - Porcine heterograft, stented or stentless
· Allografts and autografts enlarge the orifice by about 2 mm, porcine heterografts reduce valve size by about 2 mm, and mechanical valves reduce valve size by about 5-8 mm

Trends in choice of prosthesis · Age less than 55 years - Aortic allograft or pulmonary autograft

Слайд 83Prognosis
Three fourths of patients with significant aortic regurgitation

survive 5 years after diagnosis; half survive for 10 years.

Patients with mild to moderate regurgitation survive 10 years in 80-95% of the cases. Average survival after the onset of congestive heart failure (CHF) is less than 2 years.

Prognosis  Three fourths of patients with significant aortic regurgitation survive 5 years after diagnosis; half survive

Слайд 84http://www.escardio.org/guidelines-surveys/esc-guidelines/Pages/valvular-heart-disease.aspx
ESC/EACTS Guidelines on the management of va lvular

heart disease (version 2012).
The Joint Task Force on

the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS).
http://www.escardio.org/guidelines-surveys/esc-guidelines/Pages/valvular-heart-disease.aspx  ESC/EACTS Guidelines on the management of va lvular heart disease (version 2012).  The Joint

Слайд 85TAKE CARE YOUR HEART!
THANK YOU!

TAKE CARE YOUR HEART! THANK YOU!

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