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Principles of Pharmacoeconomics

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Cost DeterminationLecture 2

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Слайд 1Principles of Pharmacoeconomics
Kem P. Krueger, Pharm.D., Ph.D.
Kimberly Braxton Lloyd, Pharm.D.
Auburn

University
School of Pharmacy

Principles of PharmacoeconomicsKem P. Krueger, Pharm.D., Ph.D.Kimberly Braxton Lloyd, Pharm.D.Auburn University School of Pharmacy

Слайд 2Cost Determination
Lecture 2

Cost DeterminationLecture 2

Слайд 3Objectives
Compare and contrast direct, indirect, and intangible costs
Describe the relationship

between marginal and average costs
Describe the five steps involved in

determining the cost of therapy or service
ObjectivesCompare and contrast direct, indirect, and intangible costsDescribe the relationship between marginal and average costsDescribe the five

Слайд 4Objectives
Given a specific perspective, identify all relevant costs that should

be included in an analysis
Identify at least five sources of

cost data
Discuss the differences between costs and charges
Explain why discounting is necessary and perform the discounting calculation
ObjectivesGiven a specific perspective, identify all relevant costs that should be included in an analysisIdentify at least

Слайд 5Cost
Data
Measurement of resource use

Cost DataMeasurement of resource use

Слайд 6Direct Medical Costs


Cost
Data
Components of Cost
expenditures on tangible

health care products or services, which contribute to the gross

national product
Direct Medical Costs  Cost DataComponents of Costexpenditures on tangible health care products or services, which contribute

Слайд 7Direct Medical Costs
(Medications, hospital days,
tests, procedures, etc.)
Cost
Data
Components

of Cost

Direct Medical Costs (Medications, hospital days, tests, procedures, etc.)Cost DataComponents of Cost

Слайд 8Other Direct (non-medical) Costs


Cost
Data
Components of Cost
expenditures on tangible products

or services, which contribute to the gross national product. They

are needed to obtain care, but they do not directly contribute to health care.
Other Direct (non-medical) CostsCost DataComponents of Costexpenditures on tangible products or services, which contribute to the gross

Слайд 9Cost
Data
Components of Cost
Other Direct (non-medical) Costs
(transportation to the doctor’s

office, hiring a
baby sitter so a parent can visit

the doctor, etc.)
Cost DataComponents of CostOther Direct (non-medical) Costs(transportation to the doctor’s office, hiring a baby sitter so a

Слайд 10Cost
Data
Components of Cost
Indirect Costs



Unpaid resource commitment. Cost of morbidity

and mortality.

Cost DataComponents of CostIndirect CostsUnpaid resource commitment. Cost of morbidity and mortality.

Слайд 11Cost
Data
Components of Cost
Indirect Costs
(Unpaid assistance, days lost
from work,

decreased
productivity, etc.)

Cost DataComponents of CostIndirect Costs(Unpaid assistance, days lost from work, decreased productivity, etc.)

Слайд 12Intangible Costs
(Pain, suffering, etc.)
Cost
Data
Components of Cost

Intangible Costs(Pain, suffering, etc.)Cost DataComponents of Cost

Слайд 13Direct Medical Costs
(Medications, hospital days,
tests, procedures, etc.)
Intangible Costs
(Pain,

suffering, etc.)
Cost
Data
Measurement of resource use
Indirect Costs
(Unpaid assistance, days lost


from work, decreased
productivity, etc.)

Other Direct (non-medical) Costs
(transportation to the doctor’s office, hiring a
baby sitter so a parent can visit the doctor, etc.)

Direct Medical Costs (Medications, hospital days, tests, procedures, etc.)Intangible Costs(Pain, suffering, etc.)Cost DataMeasurement of resource useIndirect Costs(Unpaid

Слайд 14Cost Terminology
Variable costs vs. fixed costs
Total Cost: Sum of all

health care expenditures for entire population
Marginal Costs: The cost to

produce one more unit of outcome (i.e. the cost to successfully treat one additional patient)
Average Cost:
(total cost of treatment)
(total # of patients treated)
Link to avg cost worksheet
Cost TerminologyVariable costs vs. fixed costsTotal Cost: Sum of all health care expenditures for entire populationMarginal Costs:

Слайд 15AC
MC
Treatment
Costs
Average Vs. Marginal Costs
Proportion of Patients Treated
0.01

0.99
ACMCTreatmentCostsAverage Vs. Marginal CostsProportion of Patients Treated0.01

Слайд 16Specifying the Inputs
Develop comprehensive list of ALL relevant inputs (i.e.

resources consumed) to produce a given output or consequence
The list

will be determined by the perspective of the analysis
Common to all forms of economic evaluation

Specifying the InputsDevelop comprehensive list of ALL relevant inputs (i.e. resources consumed) to produce a given output

Слайд 17Payer Perspective
Direct





Indirect

Asthma management service

Payer PerspectiveDirectIndirectAsthma management service

Слайд 18
Hospitalizations
Laboratory costs
Medications
Medical devises
Physician / pharmacist fees
Payer Perspective
Direct





Indirect

Asthma management service
?

HospitalizationsLaboratory costsMedications Medical devisesPhysician / pharmacist feesPayer PerspectiveDirectIndirectAsthma management service?

Слайд 19Direct




Indirect (overhead / accounting costs)
Provider Perspective
Community pharmacy providing
asthma management

services
Note: Cost categories were taken from
Brad Stoltz’s 2001 Pharm.D.

project
DirectIndirect (overhead / accounting costs)Provider PerspectiveCommunity pharmacy providing asthma management servicesNote: Cost categories were taken from Brad

Слайд 20Direct




Indirect (overhead / accounting costs)
Maintenance
Utilities
Mortgage / rent
Business licenses
Office supplies
laundry,

haz. waste disposal, etc.

Equipment / leases
Fees
Education
Marketing
Dedicated personnel

Provider Perspective
Community pharmacy

providing
asthma management services

Note: Cost categories were taken from
Brad Stoltz’s 2001 Pharm.D. project

DirectIndirect (overhead / accounting costs)Maintenance UtilitiesMortgage / rentBusiness licensesOffice supplieslaundry, haz. waste disposal, etc.Equipment / leasesFeesEducationMarketing Dedicated

Слайд 21Patient Perspective
Direct






Indirect


Asthma management service

Patient PerspectiveDirect IndirectAsthma management service

Слайд 22
Co-pays,
education,
insurance premium,
transportation,
prescriptions,
sitters

missed work,
sitters
Patient

Perspective
Direct






Indirect


Asthma management service

Co-pays, education, insurance premium, transportation, prescriptions, sitters missed work, sittersPatient PerspectiveDirect IndirectAsthma management service

Слайд 23Societal Perspective
Direct






Indirect


Asthma management service

Societal PerspectiveDirectIndirectAsthma management service

Слайд 24
healthcare costs,
e.g. premiums,
Medicare & Medicaid,
Taxes,
Medication R&D,
Healthcare workforce,



lost productivity,
lost wages
Societal Perspective
Direct






Indirect


Asthma cost of illness

healthcare costs,e.g. premiums,Medicare & Medicaid, Taxes, Medication R&D, Healthcare workforce, lost productivity, lost wagesSocietal PerspectiveDirectIndirectAsthma cost of

Слайд 25Counting Units
Determine the unit of use for a given resource

(e.g., hospital day, single lab test, 30-day supply of medication)

Determine

how many units will be consumed over the study period
Counting UnitsDetermine the unit of use for a given resource (e.g., hospital day, single lab test, 30-day

Слайд 26Assigning Dollar Values
Opportunity costs Vs. market price
Personnel time / costs
Medication

costs
Physician and other services
Hospital / emergency department costs
Based upon

cost accounting system
Assigning Dollar ValuesOpportunity costs Vs. market pricePersonnel time / costsMedication costsPhysician and other servicesHospital / emergency department

Слайд 27Example of Hospital Costs and Charges

Example of Hospital Costs and Charges

Слайд 28Sources of Cost Data
Primary data collection methods
Clinical trials
Naturalistic trial /

observation cost / accounting system
Secondary data collection methods
Administrative / claims

databases
Literature / published AWP
Expert opinion
Model
Decision analytical
Statistical
Sources of Cost DataPrimary data collection methodsClinical trialsNaturalistic trial / observation cost / accounting systemSecondary data collection

Слайд 29Adjusting for Differences in the Timing of Costs
A cost or

benefit today is not equivalent in value to the same

cost or benefit in the future
Consider amount of money that would have to be set aside today to get predetermined amount in the future
What rate do you use?
Adjusting for Differences in  the Timing of CostsA cost or benefit today is not equivalent in

Слайд 30Discounting
Now
Past
Future
Account for Inflation
Discount future costs

DiscountingNowPastFutureAccount for InflationDiscount future costs

Слайд 31Taken from: http://www.orst.edu/dept/pol_sci/fac/sahr/mill00.htm without permission

Taken from: http://www.orst.edu/dept/pol_sci/fac/sahr/mill00.htm without permission

Слайд 32Net Present Value (Amount equivalent to $1000 in 2000)
Go to

Discounting Worksheet

Net Present Value  (Amount equivalent to $1000 in 2000)Go to Discounting Worksheet

Слайд 33Discounting
What rate do you use?
HH Bonds
4% (fixed rate)
EE Bonds
5.73% (based

on 90% of 5 yr avg Treasury securities yield)
I Bonds:

3.6% (fixed rate +
3.89% variable (inflation-based) rate)
= 7.49%

Source: Federal Reserve Bank of New York http://www.publicdebt.treas.gov/sav/sav.htm (accessed 8/29/00)

DiscountingWhat rate do you use?HH Bonds4% (fixed rate)EE Bonds5.73% (based on 90% of 5 yr avg Treasury

Слайд 34Allowing for Uncertainty
What if the type and number of resources

included in the analysis change?

What if a different discount rate

is used?

Sensitivity analysis is the technique of systematically varying key variables in an analysis to determine if the results of the analysis change. (This will be covered later).
Allowing for UncertaintyWhat if the type and number of resources included in the analysis change?What if a

Слайд 35Purchase cable
service
Do not purchase
cable service
Example
Need
a TV
Purchase a
32”

TV
Purchase a
20” TV
Purchase cable
service
Do not purchase
cable service
Go to

cost determination worksheet
Purchase cable serviceDo not purchase cable serviceExampleNeed a TVPurchase a32” TVPurchase a20” TVPurchase cable serviceDo not purchase

Слайд 36Questions

Questions

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