Слайд 1Jsc «astana medical university»
department of inner diseases
iws
«chronic gastritis»
Done by: antikeyeva
Aliya
463 gm
Checked by: baydurin s.a.
Astana,2018
Слайд 3Etiology
Helicobacter pylori is the main reason of development of the
chronic gastritis
Слайд 5Pathogenicity of helicobacter pylori
Слайд 6Autoimmune atrophic gastritis
is a chronic inflammatory disease in which the immune
system mistakenly destroys a special type of cell (parietal cells) in the stomach. Parietal
cells make stomach acid (gastric acid) and a substance our body needs to help absorb vitamin B12 (called intrinsic factor). The progressive loss of parietal cells may lead to iron deficiency and finally vitamin B12 deficiency.
Слайд 7Process often is located in the corpus and fundus
Слайд 8Chemical reactive gastritis
Nonspecific reactive epithelial changes in response to variety
of gastric mucosal irritants.
Reasons:
Reflux of alkaline duodenal contents
Chronic usage of
NSAIDs and corticosteroids
The main sign-death of the glands of the mucous membrane. The development of hyperplasia and fibrosis
Слайд 9Lymphocytic gastritis
LG is an uncommon chronic gastritis characterized by lymphocytosis
of foveolar and surface epithelium. Etiology and pathogenesis are still
unknown. Might be due to immune reaction on unclassified antigens.
T-cell lymphocytic infiltration
Слайд 10eosinophilic gastritis
Unknown etiology. Bronchial asthma, eczema in the history
Слайд 11granulomatous gastritis
Granulomatous gastritis can be a manifestation of some systemic
diseases.
With Crohn's disease, ulceration of the mucosa, granulomas and scar
strictures are observed.
Слайд 12giant hypertrophic gastritis
Etiology and pathogenesis are unknown
Giant hypertrophic gastritis (GHG)
is a general term for inflammation of the stomach due
to the accumulation of inflammatory cells in the inner wall (mucosa) of the stomach resulting in abnormally large, coiled ridges or folds that resemble polyps in the inner wall of the stomach (hypertrophic gastric folds).
Слайд 13clinical picture
Chronic non-atrophic gastritis
1. Pain syndrome
Pain in the epigastric area
and on an empty stomach
2. Dyspeptic syndrome
heartburn, sour eructations,
nausea, vomiting with gastric acidic reaction content
Слайд 14Atrophic gastritis
+ vitamin B12 deficiency
heaviness in the epigastric area, a feeling
of overeating, stomach overflow, burping food and air, an unpleasant
aftertaste in the mouth, a decrease in appetite, flatulence, unstable stools
Слайд 15Chemical gastritis
triad of symptoms:
pain
vomiting
weight loss
Слайд 16giant hypertrophic gastritis
pain in the epigastric region,often aching
Occur after
eating, a feeling of heaviness in the stomach.
Vomiting and
diarrhea are possible.
Decreased appetite.
Losing weight.
Peripheral edema.
Слайд 17Lab and instrumental diagnostics
X-ray
with chronic violation of the patency
of the duodenum, the contrast mass is more than 45
s, the lumen expansion
Слайд 18localization in the body with a very rare spread below
it. Thickened and deformed folds are connected among themselves by
a large number of connecting paths, due to which an atypical large-scale relief is formed. By the large curvature, a coarse serration occurs.
Слайд 19fibrogastroduodenoscopy
non-atrophic gastritis. Mucous membrane is shiny, edematic, hyperemia, hemorrhages are
possible.
Слайд 20atrophic gastritis.
The mucous membrane is thinned, pale gray, with
translucent blood vessels, the relief is smoothed
Слайд 21Chemical gastritis
The gatekeeper gapes, the mucous membrane is hyperemic, edematic.
Bile in the stomach. Erosion
Слайд 22Disease Menetries.
giant folds, a lot of mucus, vulnerable mucous
membrane, erosion, hemorrhage
Слайд 23study of secretory function of the stomach
Слайд 25Differential diagnostics
Chronic multifocal atrophic gastritis
Chronic autoimmune atrophic gastritis
Stomach ulcer
Gastric adenocarcinoma