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Prescription writing

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Sources and manufacture of medicines

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Слайд 1Prescription writing

Prescription writing

Слайд 3 Sources and manufacture of medicines

Sources and manufacture of medicines

Слайд 4Medicines forms

Medicines forms

Слайд 5 Dose and unit of dose
Dose – is a amount of

medicine administrating/entering in the body.
Unit of medicine‘s dose are:


Grams

and milligrams (solid and soft forms)




2. Milliliters and drops
(liquid forms)

Dose and unit of doseDose – is a amount of medicine administrating/entering in the body. Unit of

Слайд 6What is a prescription?
Prescription – is a doctor's written request

to the pharmacy.

What is a prescription?Prescription – is a doctor's written request to the pharmacy.

Слайд 7What is the difference between next word-combination?
Pharmaceutical substance – it

is a substance for production of medicines/drug
Dosage form – the

state of the medicinal preparation corresponding to the methods of its administration and application and ensuring the achievement of the necessary therapeutic effect
Medical drug/Drug – substance in the medicinal forms, used for the prevention, diagnosis, treatment of the disease, rehabilitation, for the preservation, prevention or termination of pregnancy

What is the difference between next word-combination?Pharmaceutical substance – it is a substance for production of medicines/drugDosage

Слайд 8Basic rules of prescription writing
1. From one to three

medicines can be written on the blank №107/у-88.
2. All medicines

should be written by INN (International non-proprietary name), except Homeopathic medicines, alkaloids and medicines (substances) of plant origin.
3. Only allowed abbreviations can be used in the prescriptions.
4. Corrections in the prescription are forbidden.
5. The instruction for patient is given in his/her native language.
6. All solid medicines prescription are written only in milligram, except powder for external use (prescription in gram, word «gram» is not writing).
7. Liquid medicines for injection prescription are written in mg/ml, for internal use – milliliter (ml).
Basic rules of prescription writing 1. From one to three medicines can be written on the blank

Слайд 9Solid forms

Solid forms

Слайд 10Prescription writing of the solid forms
Classification




Prescription writing of the solid formsClassification

Слайд 11Powder
1. On the way of application

1.1. internal
for application per

os
as powder for soluble for injection
1.2. external
for application

as dusting powder

2. On the dosing method

2.1 undivided

2.2 divided

Powder  1. On the way of application1.1. internalfor application per os as powder for soluble for

Слайд 12What type of powder you can see in the prescription

writing?
It is a undivided powder.
Rp.: Magnesium hydrosilicatis 10,0
Da. Signa.

Apply the powder to the affected area of the skin twice a day.

It is a divided powder.

Rp.: Ascorbici acidi 0,05
Sacchari 0,3
M.f.pulv.
Da tales doses numero 10.
Signa. Use the powder to the oral twice a day.
.

What type of powder you can see in the prescription writing?It is a undivided powder. Rp.: Magnesium

Слайд 13Rp.: Sillicii dioxydi colloidi 50,0
D.S. Take one tablespoon three times

a day, beforehand dissolve in ½ glass of water.
Rp.:

Sillicii dioxydi colloidi 3,0
D.t.d.№10.
S. Take powder three times a day, beforehand dissolve in ½ glass of water.


Rp.: Sillicii dioxydi colloidi 50,0D.S. Take one tablespoon three times a day, beforehand dissolve in ½ glass

Слайд 14Powder for soluble for injection
Rp.: Benzylpennicillini natrii 500 000 UE
D.t.d.

№20
S. 500 000 UE i/m each 4 hour (previously) pre-dissolved

in 5 ml water for injection
Powder for soluble for injection Rp.: Benzylpennicillini natrii 500 000 UED.t.d. №20S. 500 000 UE i/m each

Слайд 15Tablets
Tablets – are the solid dosage drugs form, intended

for oral use.
Tablets are produced by compressing of substances.


Tablets Tablets – are the solid dosage drugs form, intended for oral use. Tablets are produced by

Слайд 16Prescription writing of the tablets
Detailed form
Rp.: Tabulettam Paracetamoli 500 mg.
Da

tales doses numero 10.
Signa. Take/Use one tablet oral tree times

a day.

Short form

Rp.: Tabl. Paracetamoli 500 mg.
D.t.d.№10.
S. Take/Use one tablet oral tree times a day.

Prescription writing of the tabletsDetailed formRp.: Tabulettam Paracetamoli 500 mg.Da tales doses numero 10.Signa. Take/Use one tablet

Слайд 17Prescription writing of the tablets
The first case
Rp.: Tabulettas Paracetamoli

500 mg №10.
D.S. Take one tablet oral tree times a

day.

The second case

Rp.: Tabulettas «Cyston» №10.
D.S. Take one tablet oral tree times a day.

Prescription writing of the tabletsThe first case Rp.: Tabulettas Paracetamoli 500 mg №10.D.S. Take one tablet oral

Слайд 18Capsules
- a solid dosage form in which the drug

is enclosed in a hard or soft soluble container (shell)

Capsules

are taken orally.

Capsules are usually gelatin.
Capsules - a solid dosage form in which the drug is enclosed in a hard or soft

Слайд 19Prescription writing of the capsules
The first case. Medicine is one

medical active substance.
Rp.: Tetracyclini hydrochloridi 250 mg.
Da tales doses numero

20 in capsulis gelatinosis.
Signa. Take one capsule orally three time a day.

The second case. Medicines consist of several medical substances.

Rp.: Capsules «Fenules» №20.
Da. Signa. Take one capsule orally three time a day

Prescription writing of the capsulesThe first case. Medicine is one medical active substance.Rp.: Tetracyclini hydrochloridi 250 mg.Da

Слайд 20Benefits and limitations of solid forms
Benefits
Solid forms are rather convenient

in usage.
Solid forms can be stored for a long period

of time.
Solid forms mask an unpleasant taste and odor.
Solid forms are transported easily.

Limitations

Solid forms begin to act during hour.
Solid form can not be used as medicines for ambulance.



Benefits and limitations of solid forms BenefitsSolid forms are rather convenient in usage.Solid forms can be stored

Слайд 21 Ointment. Characteristic.

Ointment. Characteristic.

Слайд 22Ointment – is a soft viscously consistency medicinal form, which

are used for external topical application.
Ointments are prepared by

mixing various medicines with ointment bases.
Ointment bases are form-building substance. They are carriers of medicines substance in ointment.
Ointment bases are divided into three groups:
Hydrophobic – vaseline, wax, vegetable oils.
Hydrophilic – collagen, agar, polymer high molecular weight compounds polyvinylpyrrolidone
Hydrophobic-hydrophilic (mix vaseline with lanoline)

Ointment – is a soft viscously consistency medicinal form, which are used for external topical application. Ointments

Слайд 23Ointment
Classification on consistency:
Ointment themselves
Cream
Paste
Gel
Liniment
Classification on use:


Dermatological
Ophthalmological
Others …

Ointment Classification on consistency: Ointment themselves CreamPaste Gel Liniment Classification on use: DermatologicalOphthalmological Others …

Слайд 24Ointment themselves Ointment are usually undosed form, therefore they prescribed in

total volume.
Prescribing 20 g officinal ointment containing 0,5

% Prednisolon.
Rp.: Unguenti Prednisoloni 0,5% - 20,0.
Da. Signa. Apply on derma 3 time a day.





Prescribing 20 g officinal ointment «Levomecol».
Rp.: Unguenti «Levomecol» 40,0.
Da. Signa. Apply on derma 3 time a day.


Ointment themselves Ointment are usually undosed form, therefore they prescribed in total volume.

Слайд 25Varieties of ointment

Rp. : Cremoris Hydrocortisoni 1% - 10,0

Da. Signa. Apply on damaged skin three time

a day.




Rp.: Gelumi Diclofenaci 1% - 30,0
Da. Signa. Apply on damaged skin three time a day.




Cream – less viscous then ointment.





Gel – less viscous and include gelatin as ointment base.






Varieties of ointmentRp. : Cremoris Hydrocortisoni 1% - 10,0    Da. Signa. Apply on damaged

Слайд 26Varieties of ointment
Paste – is a kind of ointment, containing

no less 25% but no more 65% solid substances (powder)




Rp.: Pаstae Zinci 25% - 25,0
Da. Signa. Apply on a moist area of the skin three time a day.

Varieties of ointmentPaste – is a kind of ointment, containing no less 25% but no more 65%

Слайд 27Varieties of ointment
Liniment – is a liquid ointment, has a

plant oil as a base.

Rp.: Linimenti Synthomycini 5 % -

25,0
Da. Signa. Apply on affected skin three time a day.

Varieties of ointmentLiniment – is a liquid ointment, has a plant oil as a base.Rp.: Linimenti Synthomycini

Слайд 28Suppositories

Suppositories

Слайд 29Suppositories – are dosage soft medical form
It is solid at

room temperature It is softened at body temperature
Cacao Oil is basically

used for prepared of suppositories.
There can be distinguished rectal suppositories – Suppositoria rectalia and vaginal suppositories - Suppositoria vaginalia.


Suppositories – are dosage soft medical form It is solid at room temperature It is softened at

Слайд 30Rectal suppositories
Usually dome-shaped
Suppositories mass ranged from 1,1 to 4,0
If

the mass of suppositories is not indicated in the prescription

they usually weigh 3,0.

Rp.: Suppositorium cum
Paracetamolo 250 mg
Da tales doses numero 10.
Signa. Insert one suppository rectally twice a day when fever

Vaginal suppositories

Usually spherical or egg-shaped
Suppositories mass ranged from 1,5 to 6,0
If the mass of suppositories is not indicated in the prescription they usually weigh 4,0.
Rp.: Suppositorium cum Synthomycino 250 mg
Da tales doses numero 10.
Signa. Insert one suppository vaginally twice a day


Rectal suppositories Usually dome-shapedSuppositories mass ranged from 1,1 to 4,0If the mass of suppositories is not indicated

Слайд 31Relatively rarely suppositories are prepared at the chemist. In this

case prescription should be detailed and include all used substances.
Prescribe

10 suppositories containing 0,02 grams of Promedol each. Insert rectally at the pain.

Rp.: Promedoli 0,02
Olei Cacao 3,0
Misce ut fiat suppositorium rectale.
Da tales doses numero 10.
Signa. Insert rectally at the pain.

Relatively rarely suppositories are prepared at the chemist.  In this case prescription should be detailed and

Слайд 32Aerosols

Aerosols

Слайд 33Aerosols – aerodisperse systems, consisting of 1. Dispersion medium -

containing air, gas or mixture of gas. 2. Dispersion phase containing

solid medicines (powder), liquid medicines (solution) or gaseous substances.

Rp.: Aerosolum Salmeteroli 25mkg/1 dosim – 125 doses.
D.S. Inhale three time a day.

Rp.: Aerosolum Fenoteroli 0,1 mg/1dosim – 10 ml
D.S. Inhale one dose at the asthma attack.

Two variants of prescription

Aerosols – aerodisperse systems, consisting of   1. Dispersion medium - containing air, gas or mixture

Слайд 34Other cases of prescription writing of aerosol
When aerosol contains several

medicines and has a brand-name the prescription has to be

written out on brand-name.
The name is taken in quotation marks.

Rp.: Aerosolum «Inhalypt» - 30 ml.
D.S. Inhale three time a day.


When aerosol is not dosed the prescription has to be written out with indicated the name and the volume (weight) of aerosol.

Rp.: Aerosolum «Dexpanthenol» - 150 ml.
D.S. Apply three time a day at the affected skin.

Other cases of prescription writing of aerosolWhen aerosol contains several medicines and has a brand-name the prescription

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