Parkinson 's disease : diagnosis and treatment

of 823 group
Research adviser: Kozhevnikov Sergey Pavlovich
Foreign language adviser: Trebukh

Olga Sergeevna

Udmurt State University
Institute of Natural Science
Department of Physiology, Cell biology and Biotechnology

Izhevsk, 2020

early diagnosis.

James Parkinson in 1817, which he called as trembling paralysis.
The

Parkinson 's disease (PD ) is the second of neurodegenerative diseases after Alzheimer 's disease among age-related.
Most often the first symptoms of the disease appear in 55-60 years. However, in some cases disease also can show up under the 40 of age or under the age of 20.
In Russia every year Parkinson 's disease diagnosed in almost 10 thousand people. And worldwide, Parkinsonism is sick more than 10 million people, and in the future their number could increase to 50 million by 2050.

death of black substance neurons (a special area of the

brain) and the disorders of dopamine synthesis.
Dopamine is a chemical compound to control of movements of the human body. It transmits information between black substance and other areas of the brain. It provides smooth and coordinated movements.

constraint
deceleration of movements with reduction of their amplitude
violation of

gait and body position
speech is devoid of expressiveness, monotonic and has a tends to fade
Cognitive disorders of memory and attention degradation are also characteristic
In addition to motor disorders, metabolic disorders are also observed
Also mental disorders may are present: initial signs of psychosis (fear, confusion, insomnia, hallucination, paranoia), sleep disorders and pathological fatigue

state university, the search for early markers is carried out

using EEG testing.
Electroencephalography is a method of studying of brain electrical activity. The search is carried out on EEG records at concentration of attention, at motor functions and at olfactory tests.
The resulting records are processed and compared to a group of healthy subjects.

midanthan)

brain structures in the subthalamic nucleus, in the inner segment

of the pale ball, in the nucleus of the thalamus. After implantation of electrodes into brain substance, ends are passed under skin into neck area, where they are attached to a pulse generator. For the management of parameters of stimulation used to a hand-held remote called a programmator.
After surgery, most patients remain on antiparkinsonic therapy, but its dose decreases.

no effective method of diagnosis, as well as treatment of

this neuropathology, but I hope that in the near future we will be able to change this. Solving this problem will help to avoid debilitating old age for many people, to suspend hereditary transmission to the next generations of this disease, Also It will help in the treatment of similar diseases.