PHYLOGENETIC DISORDERS OF DIGESTIVE SYSTEM

STATE MEDICAL UNIVERSITY
SIMFEROPOL, CRIMEA
STUDENT NAME :AJAY KUMAR SHARMA
GROUP: 195B
GUIDED BY:
ANNA

ZHUKOVA ALEXANDROVNA MAM

of a species or group of organisms, or of a

particular feature of an organism.

PHYLOGENETIC DISORDERS OF DIGESTIVE SYSTEM

cancer
5.Cystic fibrosis
6. Glucose galactose malabsorption
7.Wilsons disease
8.Zellweger syndrome

9.Gastrointestinal disease

Autoimmune hepatitis
14.Gastroesophageal Reflux Disease (GERD) ...
15.Gallstones. ...
16.Celiac disese ..
17.Ulcerative Colitis. ...
18.Irritable

Bowel Syndrome. ...
19.Hemorrhoids. ...
20.Diverticulitis.

of sugar (glucose) in the blood. Insulin produced by the

pancreas lowers blood glucose. Absence or insufficient production of insulin, or an inability of the body to properly use insulin causes diabetes.

lower part of the stomach (pancreas).The pancreas secretes enzymes that

aid digestion and hormones that help regulate the metabolism of sugars. This type of cancer is often detected late, spreads rapidly, and has a poor prognosis.
about 5 to 10 percent of pancreatic cancers are hereditary. This means that for every 20 people with pancreatic cancer, one or two likely have an inherited mutation that increased their risk for developing the disease.

in a million adults. The condition is caused by occlusion

of the hepatic veins that drain the liver. It presents with the classical triad of abdominal pain, ascites, and liver enlargement.
Budd- Chiari syndrome is caused by blood clots that completely or partially block blood flow from the liver. The blockage may occur anywhere from the small and large veins that carry blood from the liver (hepatic veins) to the inferior vena cava.

cancer, colon cancer, or rectal cancer, is the development of

cancer from the colon or rectum (parts of the large intestine).
A cancer is the abnormal growth of cells that have the ability to invade or spread to other parts of the body. In general, colon cancer begins when healthy cells in the colon develop changes (mutations) in their DNA. As the cells accumulate, they form a tumor. With time, the cancer cells can grow to invade and destroy normal tissue nearb.

disorder characterized by cancer of the large intestine (colon) and

rectum.
People with the classic type of familial adenomatous polyposis may begin to develop multiple noncancerous (benign) growths (polyps) in the colon as early as their teenage years.
Zellweger syndrome is a rare congenital disorder characterized by the reduction or absence of functional peroxisomes in the cells of an individual.[1] It is one of a family of disorders called Zellweger spectrum disorders which are leukodystrophies. Zellweger syndrome is named after Hans Zellweger (1909–1990), a Swiss-American pediatrician, a professor of pediatrics and genetics at the University of Iowa who researched this disorder.

absence of functional peroxisomes in the cells of an individual.[1] It is one

of a family of disorders called Zellweger spectrum disorders which are leukodystrophies. Zellweger syndrome is named after Hans Zellweger (1909–1990), a Swiss-American pediatrician, a professor of pediatrics and genetics at the University of Iowa who researched this disorder.[2][3]

lining the intestine
cannot take in the sugars glucose and

galactose, which prevents proper digestion of these
molecules and larger molecules made from them. Glucose and galactose are called simple
sugars, or monosaccharides.

Glucose-galactose malabsorption

system.Cystic fibrosis affects the cells that produce mucus, sweat, and

digestive juices. It causes these fluids to become thick and sticky. They then plug up tubes, ducts, and passageways.

CYSTIC FIBROSIS

disorder that may result in lung disease or liver disease.

Onset of lung problems is typically between 20 and 50 years old. This may result in shortness of breath, wheezing, or an increased risk of lung infections.
the signs and symptoms most people experience with this deficiency are:Chronic cough.Emphysema.COPD.Liver failure.Hepatitis.Hepatomegaly (enlarged liver) Jaundice. Cirrhosis.

bile irritates the food pipe lining. This is a chronic

disease that occurs when stomach acid or bile flows into the food pipe and irritates the lining. Acid reflux and heartburn more than twice a week may indicate GERD.
Symptoms include burning pain in the chest that usually occurs after eating and worsens when lying down.

families. People with a first-degree relative with celiac disease (parent, child,

sibling) have a 1 in 10 risk of developing celiac disease.Celiac disease can develop at any age after people start eating foods or medicines that contain gluten. Left untreated, celiac disease can lead to additional serious health problems
Celiac disease is a serious autoimmune disease that occurs in genetically predisposed people where the ingestion of gluten leads to damage in the small intestine. It is estimated to affect 1 in 100 people worldwide. Two and one-half million Americans are undiagnosed and are at risk for long-term health complications.

anus and lower rectum, similar to varicose veins. Hemorrhoids can

develop inside the rectum (internal hemorrhoids) or under the skin around the anus (external hemorrhoids).Nearly three out of four adults will have hemorrhoids from time to time. Hemorrhoids have a number of causes, but often the cause is unknown.

lining of your digestive system. They are found most often

in the lower part of the large intestine (colon). Diverticula are common, especially after age 40, and seldom cause problems.The presence of diverticula is known as diverticulosis (die-vur-tik-yoo-LOE-sis). When one or more of the pouches become inflamed, and in some cases infected, that condition is known as diverticulitis (die-vur-tik-yoo-LIE-tis). Diverticulitis can cause severe abdominal pain, fever, nausea and a marked change in your bowel habits.