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Toxoplasma gondii

MORPHOLOGYPseudocytes: intercellular collection of trophozites in macrophages and reticuloendothelial cells in the acute stage of infection.Trophozites:obligate intracellular parasites,about 6x2mm, crescent shaped with central nucleus and multiply by binary fission formind pseudocytes.

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Слайд 1Toxoplasma gondii
Name: muthusamy kalaignanaselvi kiruthika
Group no:194 b

Toxoplasma gondiiName: muthusamy kalaignanaselvi kiruthikaGroup no:194 b

Слайд 2MORPHOLOGY
Pseudocytes: intercellular collection of trophozites in macrophages and reticuloendothelial cells

in the acute stage of infection.
Trophozites:obligate intracellular parasites,about 6x2mm, crescent

shaped with central nucleus and multiply by binary fission formind pseudocytes.


MORPHOLOGYPseudocytes: intercellular collection of trophozites in macrophages and reticuloendothelial cells in the acute stage of infection.Trophozites:obligate intracellular

Слайд 3Cysts: collection of trophozites (cystozoites-bradyzoites) enclosed in a true tissue

cyst,in chronic stage or latent infection when immunity develops .
Oocysts:oval,10x12mm,contains

two sporocysts each containing four sporozoites,and found in stools of infected cats
Cysts: collection of trophozites (cystozoites-bradyzoites) enclosed in a true tissue cyst,in chronic stage or latent infection when

Слайд 4Life cycle

Life cycle

Слайд 5In cats and other felines when cats ingest pseudocyst,cysts,a cycle

of schizogony and gametogony takes place in intestinal epithelium with

resultant Formation of oocysts that are excreted in stools
In cats and other felines when cats ingest pseudocyst,cysts,a cycle of schizogony and gametogony takes place in

Слайд 6In man and other animals : ingestion of pseudocyst or

oocysts does not results in an intestinal cycle ,bit exTraintestinal

Development brakes place with formation of pseudocyst and cysts in viscera ,muscles and brain
In man and other animals : ingestion of pseudocyst or oocysts does not results in an intestinal

Слайд 7Human infection takes place

Human infection takes place

Слайд 8Ingestion of undercooked infection meat cysts and paeudocysts

Ingestion of undercooked infection meat cysts and paeudocysts

Слайд 9Contamination of water or food with infected cats feces

Contamination of water or food with infected cats feces

Слайд 10Transplacental (congential)

Transplacental (congential)

Слайд 11Contamination of mucous memberanes with trophozites (laboratory infection)

Contamination of mucous memberanes with trophozites (laboratory infection)

Слайд 12Pathogenicity
Chronic toxoplasmosis

PathogenicityChronic toxoplasmosis

Слайд 13The commonest form without symptoms,or with chorioretinitis ; detected by

the presence of antibodies in the serum.persons with latent from

when subjected to immunosuppression from what ever cause (immunosuppressive therapy or infection as aids)may develop acute symptomatic infection

The commonest form without symptoms,or with chorioretinitis ; detected by the presence of antibodies in the serum.persons

Слайд 14In woman who are infected for first time in first

four months of pregnancy,the fetus may become infected.the baby may

be aborted or does shortly after birth.live infants show signs of congenital toxoplasmosis: hydrocephalus, encephalitis, chorioretinitis and cerebral classification. Maternal antibodies when present(acquired before pregnancy)protect the fetus

In woman who are infected for first time in first four months of pregnancy,the fetus may become

Слайд 15Acute symptomatic toxoplasmosis may present as
Exanthaematous form:typhus fever with

rash and enlarged lyumph nodes
Lymphatic form: enlarged lymph nodes ,liver

and spleen similar to glandular fever
Cerebrospinal form: meningoencphalitis.
Acute symptomatic toxoplasmosis may present as Exanthaematous form:typhus fever with rash and enlarged lyumph nodesLymphatic form: enlarged

Слайд 16Diagnosis

Diagnosis

Слайд 17Frencel intradermal test
Serological tests
Isolation of parasite by inoculation of

laboratory animal with biospy Material

Frencel intradermal testSerological tests Isolation of parasite by inoculation of laboratory animal with biospy Material

Слайд 18Prevention and control

Prevention and control

Слайд 19Through cooking of any type of meat. Freezing of meat

to -20degree for 2days may kill the cysts.
Care in handling

meat
Care in handling cats
Avoid contamination of food and drink with cat feces.oocyts in cat feces can remain infective for a long period.
Through cooking of any type of meat. Freezing of meat to -20degree for 2days may kill the

Слайд 20Thank for your attention

Thank for your attention

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