Слайд 1Toxoplasma gondii
Name: muthusamy kalaignanaselvi kiruthika
Group no:194 b
Слайд 2MORPHOLOGY
Pseudocytes: intercellular collection of trophozites in macrophages and reticuloendothelial cells
in the acute stage of infection.
Trophozites:obligate intracellular parasites,about 6x2mm, crescent
shaped with central nucleus and multiply by binary fission formind pseudocytes.
Слайд 3Cysts: collection of trophozites (cystozoites-bradyzoites) enclosed in a true tissue
cyst,in chronic stage or latent infection when immunity develops .
Oocysts:oval,10x12mm,contains
two sporocysts each containing four sporozoites,and found in stools of infected cats
Слайд 5In cats and other felines when cats ingest pseudocyst,cysts,a cycle
of schizogony and gametogony takes place in intestinal epithelium with
resultant Formation of oocysts that are excreted in stools
Слайд 6In man and other animals : ingestion of pseudocyst or
oocysts does not results in an intestinal cycle ,bit exTraintestinal
Development brakes place with formation of pseudocyst and cysts in viscera ,muscles and brain
Слайд 8Ingestion of undercooked infection meat cysts and paeudocysts
Слайд 9Contamination of water or food with infected cats feces
Слайд 11Contamination of mucous memberanes with trophozites (laboratory infection)
Слайд 12Pathogenicity
Chronic toxoplasmosis
Слайд 13The commonest form without symptoms,or with chorioretinitis ; detected by
the presence of antibodies in the serum.persons with latent from
when subjected to immunosuppression from what ever cause (immunosuppressive therapy or infection as aids)may develop acute symptomatic infection
Слайд 14In woman who are infected for first time in first
four months of pregnancy,the fetus may become infected.the baby may
be aborted or does shortly after birth.live infants show signs of congenital toxoplasmosis: hydrocephalus, encephalitis, chorioretinitis and cerebral classification. Maternal antibodies when present(acquired before pregnancy)protect the fetus
Слайд 15Acute symptomatic toxoplasmosis may present as
Exanthaematous form:typhus fever with
rash and enlarged lyumph nodes
Lymphatic form: enlarged lymph nodes ,liver
and spleen similar to glandular fever
Cerebrospinal form: meningoencphalitis.
Слайд 17Frencel intradermal test
Serological tests
Isolation of parasite by inoculation of
laboratory animal with biospy Material
Слайд 19Through cooking of any type of meat. Freezing of meat
to -20degree for 2days may kill the cysts.
Care in handling
meat
Care in handling cats
Avoid contamination of food and drink with cat feces.oocyts in cat feces can remain infective for a long period.