My Current Research

Содержание

1. My Current Research
2. The field of science Biochemistry is the
3. History of biochemistryIt is a comparatively
4. Work in LaboratoryI conduct my research in
5. My Responsibilities as an assistant areto write
6. The subject of my research isarginase activity
7. My research problem Oxidative stress is characterized
8. Cardiovascular diseases are the leading cause of
9. Postpericardiotomy syndrome (PPS) is a medical syndrome
10. Actions of arginaseArginase is a member of
11. The purpose of my current research is
12. Materials and methods Patients/blood samples were collected
13. Concept of my research
14. Results We have come to the conclusion
15. ConclusionsUnderstanding the mechanisms that underlie the initiation
16. Thanks for attention!
17. Скачать презентанцию

The field of science Biochemistry is the study of chemical composition of living cells and chemical processes within living system.

Слайды и текст этой презентации

Слайд 1My Current Research
Southern Federal University
Academy of Biology and Biotechnology

Department of Biochemistry and Microbiology
Dzreyan V. A.

My Current Research Southern Federal UniversityAcademy of Biology and Biotechnology Department of Biochemistry and Microbiology Dzreyan V.

Слайд 2The field of science
Biochemistry is the study of chemical

composition of living cells and chemical processes within living system.

The field of science Biochemistry is the study of chemical composition of living cells and chemical processes

Слайд 3 History of biochemistry
It is a comparatively new branch of

science. Biochemistry originated in the late 19th century as a

product of chemistry and biology. Nowadays, it is а developing and promising science. Biochemistry has advanced, especially since the mid-20th century, with the development of new techniques, such as chromatography, spectroscopy, electron microscopy and so on.

Anselme Payen

Known for discovered the
First enzyme amilase,
in 1833.

Known for his discoveries of the urea cycle and the citric acid cycle (Krebs cycle).

Sir Hans Adolf Krebs

James Watson

Known as one of the co-discoverers of the structure of DNA in 1953 with F. Crick and R. Franklin.

History of biochemistryIt is a comparatively new branch of science. Biochemistry originated in the late 19th

Слайд 4Work in Laboratory
I conduct my research in the Laboratory of

Molecular Biology
at the Department of Biochemistry and Microbiology
Academy

of Biology and Biotechnology,
Southern Federal University

Work in LaboratoryI conduct my research in the Laboratory of Molecular Biology at the Department of Biochemistry

Слайд 5My Responsibilities as an assistant are
to write of reports;
to work

with equipment;
to buy some chemical reagents;
to do some calculations and

measurements;
to prepare biological samples;
to take part in scientific conferences and seminars.

My Responsibilities as an assistant areto write of reports;to work with equipment;to buy some chemical reagents;to do

Слайд 6The subject of my research is
arginase activity in the pathogenesis

of oxidative stress in patients with ischaemic heart disease and

postpericardicotomy syndrome

The subject of my research isarginase activity in the pathogenesis of oxidative stress in patients with ischaemic

Слайд 7My research problem
Oxidative stress is characterized by disbalance between

the reactive oxygen species (ROS) generation and the work of

antioxidants in the living system.
These conditions are implicated in a variety of pathologies, such as diabetes, inflammation, pulmonary hypertension, cardiovascular diseases and so on.

ROS

antioxidants

My research problem Oxidative stress is characterized by disbalance between the reactive oxygen species (ROS) generation and

Слайд 8Cardiovascular diseases are the leading cause of death globally.
The

causes, prevention, and/or treatment of all forms of cardiovascular disease

are active fields of biomedical research.

Cardiovascular diseases are the leading cause of death globally. The causes, prevention, and/or treatment of all forms

Слайд 9Postpericardiotomy syndrome (PPS) is a medical syndrome referring to an

immune phenomenon that occurs days to months (usually 1–6 weeks)

after surgical incision of the pericardium. PPS can also be caused after a trauma, after coronary intervention.
One problem with this definition is that it is so non specific.

Postpericardiotomy syndrome (PPS) is a medical syndrome referring to an immune phenomenon that occurs days to months

Слайд 10Actions of arginase
Arginase is a member of the ureohydrolase family

of enzymes. Specifically arginase converts L-arginine into urea and L

– ornithine.

arginase

urea

L – ornithine

NO -synthase

NO*

L-arginine

Слайд 11The purpose of my current research is
to evaluate arginase

activity of blood during oxidative stress and subsequent effect on

nitric oxide availability and, as a result, role of arginase activity in the pathogenesis of myocardial dysfunction.

The purpose of my current research is to evaluate arginase activity of blood during oxidative stress and

Слайд 12Materials and methods
Patients/blood samples were collected in heparinized tubes from

pediatrics patients with ischaemic heart disease and postpericardicotomy syndrome.
In my

research I employ methods of the determination of arginase activity and concentration of urea. It is a specific colorimetric assay for the determination of arginase activity based on the ornithine–ninhydrin reaction.

Materials and methods Patients/blood samples were collected in heparinized tubes from pediatrics patients with ischaemic heart disease

Слайд 13Concept of my research

Ischaemic heart disease
Increased arginase activity
Uncoupling NO synthase
Generation of

superoxide, peroxynitrite and less NO

Myocardial dysfunction (Cell death)

Concept of my research Ischaemic heart diseaseIncreased arginase activityUncoupling NO

Слайд 14Results
We have come to the conclusion that arginase activity

in the pathogenesis of myocardial dysfunction plays a significant toxic

role.
This information is important for identify the causes and cures to reduce injury.

Results We have come to the conclusion that arginase activity in the pathogenesis of myocardial dysfunction plays

Слайд 15Conclusions
Understanding the mechanisms that underlie the initiation of vascular injury

is a critical step toward developing new therapies.
Arginase inhibitors are

a potential drugs during cardiovascular diseases to reduce injury.
This concept will be developed in the subsequent research .

ConclusionsUnderstanding the mechanisms that underlie the initiation of vascular injury is a critical step toward developing new

Слайд 16Thanks for attention!

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My Current Research

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Слайды и текст этой презентации

Слайд 1My Current Research
Southern Federal University
Academy of Biology and Biotechnology

Department of Biochemistry and Microbiology
Dzreyan V. A.

Слайд 2The field of science
Biochemistry is the study of chemical

composition of living cells and chemical processes within living system.

Слайд 3 History of biochemistry
It is a comparatively new branch of

science. Biochemistry originated in the late 19th century as a

Слайд 4Work in Laboratory
I conduct my research in the Laboratory of

Molecular Biology
at the Department of Biochemistry and Microbiology
Academy

Слайд 5My Responsibilities as an assistant are
to write of reports;
to work

with equipment;
to buy some chemical reagents;
to do some calculations and

Слайд 6The subject of my research is
arginase activity in the pathogenesis

of oxidative stress in patients with ischaemic heart disease and

Слайд 7My research problem
Oxidative stress is characterized by disbalance between

the reactive oxygen species (ROS) generation and the work of

Слайд 8Cardiovascular diseases are the leading cause of death globally.
The

causes, prevention, and/or treatment of all forms of cardiovascular disease

Слайд 9Postpericardiotomy syndrome (PPS) is a medical syndrome referring to an

immune phenomenon that occurs days to months (usually 1–6 weeks)

Слайд 10Actions of arginase
Arginase is a member of the ureohydrolase family

of enzymes. Specifically arginase converts L-arginine into urea and L

Слайд 11The purpose of my current research is
to evaluate arginase

activity of blood during oxidative stress and subsequent effect on

Слайд 12Materials and methods
Patients/blood samples were collected in heparinized tubes from

pediatrics patients with ischaemic heart disease and postpericardicotomy syndrome.
In my

Слайд 13Concept of my research

Ischaemic heart disease
Increased arginase activity
Uncoupling NO synthase
Generation of

Слайд 14Results
We have come to the conclusion that arginase activity

in the pathogenesis of myocardial dysfunction plays a significant toxic

Слайд 15Conclusions
Understanding the mechanisms that underlie the initiation of vascular injury

is a critical step toward developing new therapies.
Arginase inhibitors are

Слайд 16Thanks for attention!

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My Current Research

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Слайды и текст этой презентации

Слайд 1My Current Research Southern Federal UniversityAcademy of Biology and Biotechnology

Department of Biochemistry and Microbiology Dzreyan V. A.

Слайд 2The field of science Biochemistry is the study of chemical

composition of living cells and chemical processes within living system.

Слайд 3 History of biochemistryIt is a comparatively new branch of

science. Biochemistry originated in the late 19th century as a

Слайд 4Work in LaboratoryI conduct my research in the Laboratory of

Molecular Biology at the Department of Biochemistry and Microbiology Academy

Слайд 5My Responsibilities as an assistant areto write of reports;to work

with equipment;to buy some chemical reagents;to do some calculations and

Слайд 6The subject of my research isarginase activity in the pathogenesis

of oxidative stress in patients with ischaemic heart disease and

Слайд 7My research problem Oxidative stress is characterized by disbalance between

the reactive oxygen species (ROS) generation and the work of

Слайд 8Cardiovascular diseases are the leading cause of death globally. The

causes, prevention, and/or treatment of all forms of cardiovascular disease

Слайд 9Postpericardiotomy syndrome (PPS) is a medical syndrome referring to an

immune phenomenon that occurs days to months (usually 1–6 weeks)

Слайд 10Actions of arginaseArginase is a member of the ureohydrolase family

of enzymes. Specifically arginase converts L-arginine into urea and L

Слайд 11The purpose of my current research is to evaluate arginase

activity of blood during oxidative stress and subsequent effect on

Слайд 12Materials and methods Patients/blood samples were collected in heparinized tubes from

pediatrics patients with ischaemic heart disease and postpericardicotomy syndrome.In my

Слайд 13Concept of my research

Ischaemic heart diseaseIncreased arginase activityUncoupling NO synthaseGeneration of

Слайд 14Results We have come to the conclusion that arginase activity

in the pathogenesis of myocardial dysfunction plays a significant toxic

Слайд 15ConclusionsUnderstanding the mechanisms that underlie the initiation of vascular injury

is a critical step toward developing new therapies.Arginase inhibitors are

Слайд 16Thanks for attention!

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Обратная связь

Что такое TheSlide.ru?

Слайд 1My Current Research
Southern Federal University
Academy of Biology and Biotechnology

Department of Biochemistry and Microbiology
Dzreyan V. A.

Слайд 2The field of science
Biochemistry is the study of chemical

Слайд 3 History of biochemistry
It is a comparatively new branch of

Слайд 4Work in Laboratory
I conduct my research in the Laboratory of

Molecular Biology
at the Department of Biochemistry and Microbiology
Academy

Слайд 5My Responsibilities as an assistant are
to write of reports;
to work

with equipment;
to buy some chemical reagents;
to do some calculations and

Слайд 6The subject of my research is
arginase activity in the pathogenesis

Слайд 7My research problem
Oxidative stress is characterized by disbalance between

Слайд 8Cardiovascular diseases are the leading cause of death globally.
The

Слайд 10Actions of arginase
Arginase is a member of the ureohydrolase family

Слайд 11The purpose of my current research is
to evaluate arginase

Слайд 12Materials and methods
Patients/blood samples were collected in heparinized tubes from

pediatrics patients with ischaemic heart disease and postpericardicotomy syndrome.
In my

Ischaemic heart disease
Increased arginase activity
Uncoupling NO synthase
Generation of

Слайд 14Results
We have come to the conclusion that arginase activity

Слайд 15Conclusions
Understanding the mechanisms that underlie the initiation of vascular injury

is a critical step toward developing new therapies.
Arginase inhibitors are