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Hepatitis C

Hepatitis C is an infectious disease affecting primarily the liver, caused by the hepatitis C virus. The infection is often a symptomatic, but chronic infection can lead to and ultimately to cirrhosis of the liver.

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Слайд 1Hepatitis C
Execute: Kiyamov A.
Spilnik T.

Hepatitis CExecute: Kiyamov A.Spilnik T.

Слайд 2Hepatitis C is an infectious disease affecting primarily the liver, caused by the hepatitis C

virus. The infection is often a symptomatic, but chronic infection

can lead to and ultimately to cirrhosis of the liver.
Hepatitis C is an infectious disease affecting primarily the liver, caused by the hepatitis C virus. The infection is often a symptomatic,

Слайд 3Hepatitis is spread by blood-to-blood contact. It associated with intravenous drug

use, bad sterilized medical equipment.
Around 130–170 million people in world are

infected with hepatitis C.

 No vaccine against hepatitis C is currently.
Hepatitis is spread by blood-to-blood contact. It associated with intravenous drug use, bad sterilized medical equipment.Around 130–170 million people

Слайд 4Signs and symptoms
Acute infection
Hepatitis C infection causes acute symptoms in

15% of cases. Symptoms are generally mild and vague, including a

decreased appetite, fatigue, nausea, muscle or joint pains, and weight loss. 
Signs and symptomsAcute infectionHepatitis C infection causes acute symptoms in 15% of cases. Symptoms are generally mild and

Слайд 5Chronic infection
About 80% of those exposed to the virus develop

a chronic infection.

Hepatitis C after many years becomes the primary

cause of cirrhosis and liver cancer. 

Liver cirrhosis may lead to portal hypertension, ascites , varices, jaundice, and hepatic encephalopathy.
Chronic infectionAbout 80% of those exposed to the virus develop a chronic infection.Hepatitis C after many years

Слайд 6Transmission
The primary methods of transmission in the developed world is intravenous drug use,

while in the developing world the main methods are blood transfusions and unsafe medical

procedures. The cause of transmission remains unknown in 20% of cases.
TransmissionThe primary methods of transmission in the developed world is intravenous drug use, while in the developing world the main methods are blood

Слайд 7Intravenous drug use
Prevalences of hepatitis C in the intravenous drug

user population of between 60% and 80%.

Intravenous drug usePrevalences of hepatitis C in the intravenous drug user population of between 60% and 80%.

Слайд 8Blood transfusion, transfusion of blood products, or organ transplantation without HCV screening,

reuse of needles and syringes, multiple-use medication vials, infusion bags,

and bad sterilized surgical equipment carry significant risks of infection.
Blood transfusion, transfusion of blood products, or organ transplantation without HCV screening, reuse of needles and syringes, multiple-use medication

Слайд 9Body piercings
Tattooing or piercings is associated with increased risk of hepatitis

C. This can be due to improperly sterilized equipment or contamination

of the dyes.
Body piercingsTattooing or piercings is associated with increased risk of hepatitis C. This can be due to improperly sterilized

Слайд 10Personal care items
Personal care items such as razors, toothbrushes, and

manicuring or pedicuring things can be contaminated with blood.  Hepatits

is not spread through casual contact, such as hugging, kissing ang e.g.
Personal care itemsPersonal care items such as razors, toothbrushes, and manicuring or pedicuring things can be contaminated

Слайд 11Vertical transmission
Vertical transmission of hepatitis C from an infected mother to

her child occurs in less than 10% of pregnancies. There

are no measures that alter this risk.
Vertical transmissionVertical transmission of hepatitis C from an infected mother to her child occurs in less than 10%

Слайд 12Diagnosis
There are a number of diagnostic tests for hepatitis C

including

Liver biopsies are used to determine the degree of liver damage

present

There are a blood tests that try to determine the degree of hepatic fibrosis.
DiagnosisThere are a number of diagnostic tests for hepatitis C includingLiver biopsies are used to determine the degree

Слайд 13Treatment HCV induces chronic infection in 50–80% of infected persons. In

rare cases, infection can clear without treatment. Those with chronic

hepatitis C are advised to avoid alcohol and medications toxic to the liver, and to be vaccinated for hepatitis A and hepatitis B. here are about one hundred medications in development for hepatitis C.
Treatment HCV induces chronic infection in 50–80% of infected persons. In rare cases, infection can clear without treatment.

Слайд 14Epidemiology
It is estimated that 130–170 million people, or ~3% of the

world's population, are living with chronic hepatitis C. About 3–4 million

people are infected per year, and more than 350,000 people die yearly from hepatitis C.


World Hepatitis Day, held on July 28, is coordinated by the World Hepatitis Alliance.
EpidemiologyIt is estimated that 130–170 million people, or ~3% of the world's population, are living with chronic hepatitis

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