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Department of history of medicine

Gerhard DomagkGerhard Johannes Paul Domagk (30 October 1895 – 24 April 1964) was a German pathologist and bacteriologist. He is credited with the discovery of Sulfonamidochrysoidine (KI-730), the first commercially available antibiotic and marketed under the brand name Prontosil,

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Слайд 1Department of history of medicine
Name:- Abdelgalil Mohamed Mostafa Elsayed

Group:- 19ЛС2(а)‬‏

Department of history of medicineName:- Abdelgalil Mohamed Mostafa ElsayedGroup:- 19ЛС2(а)‬‏

Слайд 2Gerhard Domagk
Gerhard Johannes Paul Domagk
 (30 October 1895 – 24 April

1964) was a German pathologist and bacteriologist.
He is credited with the discovery of

Sulfonamidochrysoidine (KI-730), the first commercially available antibiotic and marketed under the brand name Prontosil, for which he received the 1939 Nobel Prize in Physiology or Medicine
Gerhard DomagkGerhard Johannes Paul Domagk (30 October 1895 – 24 April 1964) was a German pathologist and bacteriologist. He is credited with

Слайд 3Biography
Education
Domagk was born in Lagow, Brandenburg, the son of a

school headmaster. Until he was 14, he attended school in

Sommerfeld (now Lubsko, Poland). Domagk studied medicine at the University of Kiel, but volunteered to serve as a soldier in World War I, where he was wounded in December 1914, working the rest of the war as a medic. After the war, he finished his studies, and worked at the University of Greifswald, where he researched infections caused by bacteria.
BiographyEducationDomagk was born in Lagow, Brandenburg, the son of a school headmaster. Until he was 14, he

Слайд 4Career
In 1925, he followed his professor Walter Gross to the University

of Münster (WWU) and became a professor there himself. He also

started working at the Bayer laboratories at Wuppertal. The same year, he married Gertrud Strube (1897–1985). Later they would have three sons and a daughter.
Domagk was appointed director of Bayer's Institute of Pathology and Bacteriology, where he continued the studies of Josef Klarer and Fritz Mietzsch, based on works by Paul Ehrlich, to use dyes, at that time a major product of IG Farben, as antibiotics. He found the sulfonamide Prontosil to be effective against streptococcus, and treated his own daughter with it, saving her the amputation of an arm.

CareerIn 1925, he followed his professor Walter Gross to the University of Münster (WWU) and became a professor there

Слайд 5In 1939, Domagk received the Nobel Prize in Medicine for this discovery,

the first drug effective against bacterial infections. He was forced by

the Nazi regime to refuse the prize and was arrested by the Gestapo and detained for a week. (This was because the Nazi-critical Carl von Ossietzky had won the Nobel Peace Prize in 1935, which had angered the German government and resulted in German nationals not being permitted by law to accept the Nobel Prize.) In the same year, Domagk was also awarded the Cameron Prize for Therapeutics of the University of Edinburgh.

In 1939, Domagk received the Nobel Prize in Medicine for this discovery, the first drug effective against bacterial infections. He

Слайд 6contribution to medicine
Domagk earned a medical degree from the University

of Kiel in 1921. He briefly taught at the University

of Greifswald (1924–25) before joining the faculty of the University of Münster. In 1927 he became director of the I.G. Farbenindustrie (Bayer) Laboratory for Experimental Pathology and Bacteriology in Elberfeld (now in Wuppertal). There, inspired by the ideas of Paul Ehrlich, he began testing newly developed dyes for their possible effects against various infections.
contribution to medicineDomagk earned a medical degree from the University of Kiel in 1921. He briefly taught

Слайд 7He noticed the antibacterial action of one of the dyes

against streptococcal infection in mice. The dye, Prontosil red, was then tried clinically

against streptococcal infections in humans with great success. The active component of Prontosil turned out to be sulfanilamide, which became another important sulfa drug.
Unable to accept the Nobel award at the time because of Nazi German policy, Domagk later (1947) received the gold medal and diploma. He also was active in research on tuberculosis and cancer.

He noticed the antibacterial action of one of the dyes against streptococcal infection in mice. The dye, Prontosil red, was

Слайд 8Conclusion
Gerhard Domagk is one of the most prominent and most

important scientists in history who contributed in many fields, especially

the medical field, which was credited with inventing antibiotics, which are considered one of the most important materials used in the medical field to this day.
ConclusionGerhard Domagk is one of the most prominent and most important scientists in history who contributed in

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