Слайд 1Postpartum	infection
Teacher: Kamilova Irina Kaharovna
Student: Sulur PerumalSwamy Venkatesh Prabhu
Group: 163(B)-CO-LA1 Course:
                                                            
                                    
5
Date: 5-10-2020 Year: 2020-2021 Batch
                                                                    
                            							
							
							
						 
											
                            Слайд 2Postpartum	infection	–	is a septic wound infection distinguished by anatomic features of
                                                            
                                    
female reproductive organs and their functional status during pregnancy.
                                                                    
                            							
														
						 
											
                            Слайд 3Classification	principles
-	By	prevalence:	local, generalized forms.
-	By	infection	localization:	vagina, uterus, ovaries, parametric tissue, pelvis minor veins,
                                                            
                                    
mammary gland.
- By	infection	type:	aerobic (enterococci, Escherichia coli, Klebsiella, group B streptococci,
                                    staphylococci); anaerobic (Bacteroids, fusobacteria, peptococci, peptostreptococcus); gram-positive, gram- negative, mycoplasma, Chlamydia, fungi.
                                
                            							
														
						 
											
                            Слайд 4Factors	making	patients susceptible	to	infection
Changes in vaginal biocenose in final stages of pregnancy.
Pregnancy-related
                                                            
                                    
immunodeficiency development. Delivery type.
                                                                    
                            							
														
						 
											
                            Слайд 5Sponsored
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                            Слайд 6Important!!!
 In the postpartum period the intra- uterine wall is
                                                            
                                    
a traumatic surface easily infected by the spread of pathogenic
                                    and opportunistic pathogenic flora.
                                
                            							
														
						 
											
                            Слайд 7Etiology
Iron-deficiency anemia. Gestosis.
Placental presentation. Pyelonephritis.
Prolonged labour. Prolonged anhydrous term. Serious
                                                            
                                    
loss of blood.
Genital tract wounds. Surgical procedures.
                                                                    
                            							
														
						 
											
                            Слайд 8Postpartum	ulcer	–	is caused by contamination of abrasions, fissures, ruptures of vulval
                                                            
                                    
and vaginal mucous membranes.
The patient’s general condition is satisfactory.
                                                                    
                            							
														
						 
											
                            Слайд 9Diagnostics
Hyperemia. Edema.
Necrotic or purulent wound incrustation.
                            							
														
						 
											
                            Слайд 10Treatment
The wounds are cleansed with antiseptics locally (hydrogen peroxide, furacilin,
                                                            
                                    
chlorhexidine, dioxidine, hypertonic solution).
Wound debridement with proteolytic ferments is performed
                                    (tripsin, chemotripsin).
After the wound has been cleansed from pus, ointment bandages are applied (levomicole, dioxicole).
                                
                            							
														
						 
											
                            Слайд 11Postpartum
endomyometritis.
The most common infection in the postpartum period!
                            							
														
						 
											
                            Слайд 12CLINICAL	SYMPTOMS.
ACUTE FORM.
Temperature elevation › 38° on 2-5th day following delivery.
Chills.
Abdominal
                                                            
                                    
pain.
Foul-smelling, pus-containing lochia.
Headache.
Facial hyperemia.
Postpartum psychosis (the degree depends on the
                                    level of intoxication).
                                
                            							
														
						 
											
                            Слайд 13DIAGNOSTICS
Bimanual examination (the uterus is enlarged, painful, softened, contractive movements
                                                            
                                    
are restricted).
Clinical blood count. Ultrasonography.
Thermometry.
Bacterioscopic and bacteriological analysis of vaginal
                                    discharge.
Biochemical blood test (c-reactive protein increase, hypoproteinemia, hypoalbuminemia).
Coagulogram. Hysteroscopy.
Clinical urine analysis.
                                
                            							
														
						 
											
                            Слайд 14TREATMENT
Bed rest.
Antibiotic therapy (semisynthetic penicillin, combination of cephalosporin and metronidazole).
Infusion
                                                            
                                    
therapy (combination of colloids and crystalloids).
10% calcium gluconate,	10 ml i.v.
                                    Vitamin therapy.
Spasmolytics (no-spa, papaverine hydrochloride).
Immunomodulators.
Intrauterine lavage with antiseptic
                                
                            							
														
						 
											
                            Слайд 15Important!!!
If the examination reveals placental tissues or membranes in the
                                                            
                                    
uterine cavity, it is necessary to perform curettage or vacuum
                                    aspiration of the uterus.
LOW-GRADE ENDOMYOMETRITIS progresses without pronounced clinical symptoms. The onset of the disease is normally on the 7-9th day following delivery. The most common causes of the disease are Chlamydia or mycoplasma infections.
                                
                            							
														
						 
											
                            Слайд 16  Postpartum	salpingo-
oophoritis	is rarely observed. The ovaries are normally affected
                                                            
                                    
on one side. The clinical history of the disease is
                                    similar to manifestations of endomyometritis, which is followed by salpingo-oophoritis
                                
                            							
														
						 
											
                            Слайд 17 Postnatal	parametritis	– the process normally begins when lacerations or infections
                                                            
                                    
of the cervix are present.
Lateral parts of parametrium are commonly
                                    affected.
                                
                            							
														
						 
											
                            Слайд 18Clinical	symptoms
Chills on the 10-12th day following delivery.
Temperature elevation to 39
                                                            
                                    
- 40°. Tensive lower abdominal pain.
Acruturesis or dyschezia in cases
                                    when the process has spread to front or back parametrium.
                                
                            							
														
						 
											
                            Слайд 19 On bimanual examination a painful infiltrate is found in
                                                            
                                    
the fornices, the fornices are shortened.
 For diagnostics and treatment
                                    see endomyometritis.
                                
                            							
														
						 
											
                            Слайд 20Postnatal	trombophlebitis (affecting pelvis minor veins, superficial and deep veins of
                                                            
                                    
lower limbs).
Causes
Hypercoagulation.
Vessel wall lesions.
                                                                    
                            							
														
						 
											
                            Слайд 21Clinical	symptoms
Temperature elevation.
Hyperemia and tenderness along of varix dilatated shin veins.
Edema
                                                            
                                    
(if deep veins of lower limbs are involved).
                                                                    
                            							
														
						 
											
                            Слайд 2222
Treatment
Bed rest, lower limb should be maintained uplifted.
Antibacterial therapy.
Anticoagulants: direct
                                                            
                                    
effect (heparin), indirect effect (kleksan, fraxiparin, troxevasin, aspirin).
Medicines improving rheological
                                    properties of the blood: rheopolyglukin, trental, kurantil.
Hirudotherapy.
                                
                            							
														
						 
											
                            Слайд 23Obstetric	peritonitis.
Causes.
Consequence of endomyometritis.
Perforation of inflammatory tubo-ovarian mass.
Torsion of ovarian tumor
                                                            
                                    
pedicle.
Necrosis of the subserous node of hysteromyoma.
Infected rupture of uterine
                                    sutures after caesarean section.
                                
                            							
														
						 
											
                            Слайд 24Pathogenesis
Endogenous intoxication
Generalized vascular disorders General tissue hypoxia
Metabolic disorders
Dysfunction of essential
                                                            
                                    
organs and systems Destructive changes in kidneys, pancreas, liver, small
                                    intestine
Enteroparesis
                                
                            							
														
						 
											
                            Слайд 25 Enteroparesis. Motor, secretion, and absorption functions are affected.
Significant amounts
                                                            
                                    
of protein and electrolyte containing liquid accumulate in the intestinal
                                    lumen. Overdistension and ischemia of the intestinal wall cause impairment of the intestinal barrier function which leads to increased intoxication
                                
                            							
														
						 
											
                            Слайд 26Obstetric	peritonitis
phases
Reactive phase (compensatory mechanisms preserved).
Toxic phase. Terminal phase.
                            							
														
						 
											
                            Слайд 27Clinical	symptoms
psychomotor agitation
thirst
dryness of mucous membranes
general weakness
tachycardia (does not correspond to
                                                            
                                    
the body temperature)
fever
pulse rate exceeds 100bpm
shallow breathing
                                                                    
                            							
														
						 
											
                            Слайд 28unsatisfactory sleep
absence of appetite
pallor of the skin
nausea
eructation
flatulence
vomiting (not always)
the pain
                                                            
                                    
syndrome is not evident (due to
overdistension of the front abdominal
                                    wall after delivery).
                                
                            							
														
						 
											
                            Слайд 29 On palpation: the abdomen is distended, the uterus is
                                                            
                                    
enlarged, softened, the contours are indistinct, peritoneum irritation symptoms are
                                    not pronounced, sluggish peristalsis, slow flatus discharge.
                                
                            							
														
						 
											
                            Слайд 30Treatment.
Preoperative preparation (2 hours): stomach
decompression, infusion therapy intended for liquidation
                                                            
                                    
of hypovolemia and metabolic acidosis, fluid, protein and electrolytic balance
                                    correction, detoxication of the body, antibacterial therapy.
Operative treatment: hysterectomy, abdominal cavity drainage.
                                
                            							
														
						 
											
                            Слайд 31Postoperative period:
liquidation of hypovolemia and
improvement of rheological properties of the
                                                            
                                    
blood;
acidosis correction;
provision for the body’s energy demands;
antiferment and anticoagulant therapy
                                    (combination of contrical and heparin);
maintenance of artificial dieresis;
                                
                            							
														
						 
											
                            Слайд 32- antibiotic therapy;
- cardio-vascular collapse prevention and treatment;
- vitamin therapy;
-
                                                            
                                    
motor and evacuation intestinal function recovery (proserin, ganglio-blockers);
- ultraviolet irradiation
                                    of autoblood, hyperbaric oxygenation.
                                
                            							
														
						 
											
                            Слайд 33 Postpartum	sepsis	– severe non-specific infective process developing and progressing when
                                                            
                                    
normal reactivity of the organism is changed.
                                                                    
                            							
														
						 
											
                            Слайд 34Clinical	symptoms
Septicemia occurs on the 3-4th day following delivery, progresses violently.
Septicopyemia
                                                            
                                    
progresses unevenly: periods of recrudescence caused by metastatic infection and
                                    formation of new niduses are followed by periods of amelioration.
                                
                            							
														
						 
											
                            Слайд 35IMPORTANT!!!
The diagnosis is based on the following prerequisites:
- presence of
                                                            
                                    
an infection nidus;
- fever and chills;
- etiological factor was detected
                                    in blood.
                                
                            							
														
						 
											
                            Слайд 36
Impaired CNS function: euphoria, depression, sleep disturbance.
Dyspnea. Cyanosis.
Pale, grey or
                                                            
                                    
yellow skin. Tachycardia, pulse lability. Hypotension.
Enlarged liver and spleen.
                                                                    
                            							
														
						 
											
                            Слайд 37Diagnostics
Clinical blood analysis. Clinical urine analysis. Coagulogram (platelets). Blood electrolytes.
Bacteriological
                                                            
                                    
analysis. Lungs radiography.
ECG.
Blood sugar.
Acid-base condition. Central venous pressure.
Monitoring: arterial pressure,
                                    pulse rate, heart rate, body temperature.
                                
                            							
														
						 
											
                            Слайд 38Treatment
Preoperative preparation during 6-8 hours, hypervolemic hemodilution mode.
Operative treatment –
                                                            
                                    
hysterectomy and salpingectomy, abdominal cavity drainage.
                                                                    
                            							
														
						 
											
                            Слайд 39Postoperative period:
liquidation of hypovolemia and
improvement of rheological properties of the
                                                            
                                    
blood;
acidosis correction;
provision for the body’s energy demands;
antiferment and anticoagulant therapy
                                    (combination of contrical and heparin);
maintenance of artificial dieresis;
                                
                            							
														
						 
											
                            Слайд 40- antibiotic therapy;
- cardio-vascular collapse prevention and treatment;
- vitamin therapy;
-
                                                            
                                    
motor and evacuation intestinal function recovery (proserin, ganglio-blockers);
- ultraviolet irradiation
                                    of autoblood, hyperbaric oxygenation, plasmapheresis, hemosorption, hemodialysis.
                                
                            							
														
						 
											
                            Слайд 41	Postpartum	lactational	mastitis	is an inflammation of breast tissue.
The most common organism reported
                                                            
                                    
in mastitis is Staphylococcus aureus, Streptococcus is less common.
The organisms
                                    invade the breast tissue via cracking or fissures in the nipple or lactiferous ducts. Lactostasis is conducive to progressing of the inflammatory process.
                                
                            							
														
						 
											
                            Слайд 42Classification
Serous mastitis.
Infiltrative mastitis (diffuse, nodular).
Suppurative mastitis (intramammary, phlegmonous or necrotic
                                                            
                                    
suppurative, gangrenous).
                                                                    
                            							
														
						 
											
                            Слайд 43Clinical	symptoms
Rapid elevation in temperature to 39˚C. Chills.
Painful breast. Headache.
General malaise,
                                                            
                                    
weakness. Sleep disturbance.
Loss of appetite.
                                                                    
                            							
														
						 
											
                            Слайд 44Examination shows that the breast is engorged, the skin above
                                                            
                                    
the breast is hyperemic.
With the right treatment the disease is
                                    cured within 1-2 days; if inadequate therapy is chosen, the disease advances to the next (infiltrate) stage.
The	diagnosis	is made on the basis of clinical symptoms.
                                
                            							
														
						 
											
                            Слайд 45Treatment
Antibacterial therapy. Procedures against lactostasis.
Spasmolytics (no-spa) in combination with uterotonics
                                                            
                                    
(oxytocin).
Parlodel (to decrease milk production). Vitamin therapy.
Anti-staphylococcus gamma globulin, hyperimmune
                                    anti-staphylococcus plasma.
                                
                            							
														
						 
											
                            Слайд 4646
 With suppurative mastitis surgical treatment is indicated (incision of
                                                            
                                    
the abscess, bathing with
antiseptics and drainage of the pus).
 IMPORTANT!!!
                                    During		the		course of	treatment	for	postpartum	septic diseases	breastfeeding	should	be discontinued		as		the	baby	might
receive	high	doses	of	medicines with	mother’s	milk.